Results 61 to 70 of about 897,077 (404)

Delta-Tocotrienol Modulates Glutamine Dependence by Inhibiting ASCT2 and LAT1 Transporters in Non-Small Cell Lung Cancer (NSCLC) Cells: A Metabolomic Approach

open access: yesMetabolites, 2019
The growth and development of non-small cell lung cancer (NSCLC) primarily depends on glutamine. Both glutamine and essential amino acids (EAAs) have been reported to upregulate mTOR in NSCLC, which is a bioenergetics sensor involved in the regulation of
Lichchavi Dhananjaya Rajasinghe   +2 more
doaj   +1 more source

Effect of dietary &bgr;‐alanine supplementation on growth performance, meat quality, carnosine content, and gene expression of carnosine‐related enzymes in broilers

open access: yesPoultry Science, 2018
The objective of the current study was to investigate the effect of dietary &bgr;‐alanine supplementation on growth performance, meat quality, antioxidant ability, carnosine content, and gene expression of carnosine‐related enzymes in broiler chicks.
B. Qi   +5 more
semanticscholar   +1 more source

Crystallization and preliminary X-ray analysis of a D-alanyl-D-alanine ligase (EcDdlB) from Escherichia coli [PDF]

open access: yes, 2010
A recombinant form of Escherichia coli DdlB (EcDdlB) has been prepared and cocrystallized with ADP and D-alanyl-D-alanine to represent the ternary complex of EcDdlB.
Batson, Sarah   +3 more
core   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

open access: yes, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko   +2 more
core  

Exploiting molecular dynamics in Nested Sampling simulations of small peptides [PDF]

open access: yes, 2015
Nested Sampling (NS) is a parameter space sampling algorithm which can be used for sampling the equilibrium thermodynamics of atomistic systems. NS has previously been used to explore the potential energy surface of a coarse-grained protein model and has
Baldock, Robert J. N.   +4 more
core   +5 more sources

Differentiation Between Ripening Stages of Iberian Dry-Cured Ham According to the Free Amino Acids Content [PDF]

open access: yes, 2020
In this paper, the differentiation of three ripening stages, postsalting, drying, and cellar, of Iberian dry-cured ham has been carried out according to their free amino acids contents. Eighteen L-amino acids, alanine, 2-aminobutanoic acid, aspartic acid,
Alcázar Rueda, Ángela   +3 more
core   +1 more source

Alanine aminotransferase controls seed dormancy in barley

open access: yesNature Communications, 2016
Dormancy allows wild barley grains to survive dry summers in the Near East. After domestication, barley was selected for shorter dormancy periods.
Kazuhiro Sato   +9 more
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Fluctuation Effects of Magnetohydrodynamic Micro-Vortices on Odd Chirality in Magnetoelectrolysis

open access: yesMagnetochemistry, 2020
The magnetic field dependence of chiral surface formation was investigated in magnetoelectrodeposition (MED) and magnetoelectrochemical etching (MEE) of copper films.
Iwao Mogi   +2 more
doaj   +1 more source

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