Results 51 to 60 of about 109,106 (257)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Beta-alanine supplementation, muscle carnosine and exercise performance [PDF]
Purpose of review : The use of dietary supplements in sports is widespread as athletes are continuously searching for strategies to increase performance at the highest level.
Derave, Wim +2 more
core +1 more source
Microbial antibiotic resistance has become a worldwide concern, as it weakens the efficiency of the control of pathogenic microbes in both the fields of medicine and plant protection.
Yi Guan +3 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Pharmacokinetics of β-alanine using different dosing strategies [PDF]
Introduction: The ergogenic response following long-term ingestion of beta-alanine shows a high inter-individual variation. It is hypothesized that this variation is partially caused by a variable pharmacokinetic response induced by inferior dosing ...
Jan Stautemas +8 more
core +1 more source
Determination of the Stability Constant of Vanadium (V) with Alaine [PDF]
Formation equilibria of dioxy vanadium (V) complex with alanine in acidic media ...
Saeed Abedini Khorrami +3 more
doaj
Effect of salt on the growth and metabolism of Glycine max
Soybean plants cultivated with 50, 100 and 200 mM of NaCl, revealed that root growth was less affected by salinity than shoots. Salinity led to a reduction in leaf area and an increase in water content of the roots.
Helena Müller Queiroz +2 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Crystallization and preliminary X-ray analysis of a D-alanyl-D-alanine ligase (EcDdlB) from Escherichia coli [PDF]
A recombinant form of Escherichia coli DdlB (EcDdlB) has been prepared and cocrystallized with ADP and D-alanyl-D-alanine to represent the ternary complex of EcDdlB.
David I. Roper +7 more
core +2 more sources
Graphical representation of predicted dose value distribution for D-alanine-D-alanine ligase.
In this graph, x-axis represents distribution of dose value and y-axis represents fraction of compounds.
Ijaz Rasul (11841071) +5 more
core +1 more source

