Results 51 to 60 of about 1,424,492 (339)

Affected albumin endocytosis as a new neurotoxicity mechanism of amyloid beta

open access: yesAIMS Neuroscience, 2020
Senile plaques, a hallmark of Alzheimer's disease, are composed by Amyloid-Beta (Aβ). Aβ 25-35 toxicity is caused mainly by increasing reactive oxygen species (ROS), which is reversed by albumin preventing Aβ internalization.
Lourdes A. Vega Rasgado   +2 more
doaj   +1 more source

Albumin cayemite: A Negro plasma albumin variant [PDF]

open access: yesHuman Genetics, 1969
An inherited variant of human serum albumin has been found in a Negro family from Haiti. The variant is electrophoretically distinguishable from ten different previously reported types of albumin variants.
Basu, A.   +3 more
openaire   +4 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Albumin Infusion May Improve the Prognosis of Critical COVID-19 Patients with Hypoalbuminemia in the Intensive Care Unit: A Retrospective Cohort Study

open access: yesInfection and Drug Resistance, 2022
Liren Zhang,1 Weibin Yu,2 Yuwu Zhao,1 Xiaohua Chen,3 Peng Wang,3 Xiaohong Fan,4 Zhouwei Xu1 1Department of Neurology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China ...
Zhang L   +6 more
doaj  

PENGARUH PEMBERIAN SUPLEMENTASI SUPEROXIDE DISMUTASE (SOD) TERHADAP KADAR ALBUMIN SERUM PADA LANSIA [PDF]

open access: yes, 2015
Background: Levels of serum albumin can be used as a predictor of morbidity and mortality in the elderly. Reduced serum albumin concentration can be caused by oxidative modification due to aging or insufficient protein intake.
Nalaresi, Andyta   +2 more
core  

Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study [PDF]

open access: yes, 2016
Aims: Episodes of acute heart failure (AHF) unfavourably affect multiple organs, which may have an adverse impact on the outcomes. We investigated the prevalence and clinical consequences of abnormal liver function tests (LFTs) in AHF patients ...
Akhter   +20 more
core   +1 more source

Test for Albumin. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1896
Traverse City, Mich., July 28, 1896. To the Editor: —On page 1094 of ourJournalof May 30, 1896, I find a test for the detection of albumin in urine. The reagent suggested contains sodium hypochlorite, a compound known only in solution, and one that I believe can not be obtained for use as indicated in the formula.
openaire   +2 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Increased circulating levels of vitamin D binding protein in MS patients [PDF]

open access: yes, 2015
Vitamin D (vitD) low status is currently considered a main environmental factor in multiple sclerosis (MS) etiology and pathogenesis. VitD and its metabolites are highly hydrophobic and circulate mostly bound to the vitamin D binding protein (DBP) and ...
Cortese, Antonio   +9 more
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

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