Results 221 to 230 of about 381,097 (341)
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
A two-dimensional fluorescence and chemiluminescence orthogonal probe for discriminating and quantifying similar proteins. [PDF]
Li J+11 more
europepmc +1 more source
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source
Coelenterazine Analogs for Bioassays and Molecular Imaging. [PDF]
Kim SB, Kamiya G, Furuta T, Maki SA.
europepmc +1 more source
AMINO ACID COMPOSITION OF β-LACTOGLOBULIN AND BOVINE SERUM ALBUMIN
William H. Stein, William H. Stein
openalex +1 more source
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho+7 more
wiley +1 more source
Stereoselective Interactions of Chiral Polyurea Nanocapsules with Albumins. [PDF]
Zoabi A+5 more
europepmc +1 more source
Serum albumins-unusual allergens.
M. Chruszcz+5 more
semanticscholar +1 more source
Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim+10 more
wiley +1 more source
Infants and toddlers with sensitization to peanut are often co-sensitized to tree nuts. [PDF]
Meixner L+5 more
europepmc +1 more source