Results 31 to 40 of about 387,405 (380)

Increased transcription of TSPO, HDAC2, and HDAC6 in the amygdala of males with alcohol use disorder

open access: yesBrain and Behavior, 2021
Introduction Repeated exposure to high doses of alcohol triggers neuroinflammatory processes that contribute to craving and mood dysfunction in alcohol use disorder (AUD).
Luana Martins De Carvalho   +4 more
doaj   +1 more source

Increased ethanol‐inducible cytochrome P450‐2E1 and cytochrome P450 isoforms in exosomes of alcohol‐exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress

open access: yesHepatology Communications, 2017
This study investigated the role of ethanol‐inducible cytochrome P450‐2E1 (CYP2E1) in enhancing CYP2E1 and other P450 proteins in extracellular vesicles (EVs) from alcohol‐exposed rodents and human patients with alcoholism and their effects on oxidative ...
Young-Eun Cho   +5 more
semanticscholar   +1 more source

4288 Identifying Predictive Variables of High-Intensity Binge Drinking Through the Use of a Machine Learning Algorithm

open access: yesJournal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: To test if a machine learning algorithm could predict a person’s capacity to binge drink and explore what measures might be important for identifying individuals at risk for high-intensity binge drinking behaviors.
James Keoni Morris   +4 more
doaj   +1 more source

Alcohol. [PDF]

open access: yesBMJ, 1982
Abstract There is evidence for a dose-response relationship between alcohol consumption and risk of liver cirrhosis, cancers of the oropharynx, larynx, oesophagus, rectum (beer only), liver, and female breast, and violent death, but the relationship between alcohol consumption and cardiovascular disease is more complex.
openaire   +2 more sources

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

open access: yesMolecules, 2021
Alcohol consumption is associated with gut dysbiosis, increased intestinal permeability, endotoxemia, and a cascade that leads to persistent systemic inflammation, alcoholic liver disease, and other ailments.
Luis Santos-Molina   +10 more
doaj   +1 more source

Empathy [PDF]

open access: yes, 2017
A short poem about suicidal ideation and alcoholism in the United ...
Golomski, Casey
core   +2 more sources

Mechanisms of neuroimmune gene induction in alcoholism

open access: yesPsychopharmacology, 2015
RationaleAlcoholism is a primary, chronic relapsing disease of brain reward, motivation, memory, and related circuitry. It is characterized by an individual’s continued drinking despite negative consequences related to alcohol use, which is exemplified ...
F. Crews, R. Vetreno
semanticscholar   +1 more source

Socioeconomic status, BMI, and brain development in children

open access: yesTranslational Psychiatry, 2022
Low socioeconomic status (SES) in childhood is associated with deficits in executive function and changes in cortical morphology. Furthermore, rates of childhood obesity are greater among low SES children and childhood obesity is also associated with ...
Evan Dennis, Peter Manza, Nora D. Volkow
doaj   +1 more source

Correspondence between cerebral glucose metabolism and BOLD reveals relative power and cost in human brain

open access: yesNature Communications, 2019
The brain primarily uses glucose to generate energy, but the relationship of neuronal activity to glucose utilization is not necessarily a simple linear one.
Ehsan Shokri-Kojori   +5 more
doaj   +1 more source

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