Results 61 to 70 of about 325,826 (332)

A simple, highly efficient method for heterologous expression in mammalian primary neurons using cationic lipid-mediated mRNA transfection

Frontiers in Neuroscience, 2010
Expression of heterologous proteins in adult mammalian neurons is a valuable technique for the study of neuronal function. The postmitotic nature of mature neurons prevents effective DNA transfection using simple, cationic lipid-based methods.
Damian J Williams, Henry L Puhl, Stephen R Ikeda   +2 more
doaj   +1 more source

Can Parents Create Alcoholics? [PDF]

, 2011
Background: Research has shown a definitive genetic component to alcoholism, with children of alcoholic parents being much more likely to become alcoholics themselves when compared to children of non-alcoholics.
Boellner, Paul, Lang, Scott
core   +1 more source

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

ESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen, Aldina Pivodic, Maria Schaufelberger, Annika Rosengren, Michael Fu   +4 more
wiley   +1 more source

A critical analysis of COA research. [PDF]

, 1997
Five experts respected for their significant contributions to the scientific literature on children of alcoholics (COA's) offer their perspectives in a panel discussion format. The panel members reflect on the historical roots of COA research and comment
Chassin, L, Jacob, T, Johnson, JL, Schuckit, MA, Sher, KJ   +4 more
core  

Relationship between tonic and phasic craving for alcohol. [PDF]

, 2018
BackgroundMultiple measures are utilized to assess alcohol craving, often interchangeably. Little is known about the relationship between tonic and phasic craving.
Hartwell, Emily E, Ray, Lara A
core   +2 more sources

Providing Personalized Genetic Feedback for Psychiatric and Substance Use Disorders: An Urgent Need for Research

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
Danielle M. Dick, Jehannine (J9) Austin
wiley   +1 more source

A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation

ESC Heart Failure, Volume 12, Issue 2, Page 1166-1175, April 2025.
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu, Weihua Qiao, Yixuan Wang, Ying Zhou, Yin Xu, Shijie Wang, Tian Xia, Guohua Wang, Si Chen, Jiawei Shi, Nianguo Dong   +10 more
wiley   +1 more source

Aggression in War Veterans Suffering from Posttraumatic Stress Disorder with Co-morbid Alcoholism [PDF]

, 2010
For thousands of years it has been known that aggression as a symptom appears in numerous psychiatric disorders and diseases. During the last decade the appearance of the aggressive behavior related to the posttraumatic stress disorder (PTSD) has been ...
Alija Sutović, Dragan Babić, Marko Martinac, Osman Sinanović, Romana Babić, Vedran Bjelanović   +5 more
core   +1 more source

Addressing Heterogeneity in Binge Eating Disorder: A Cluster Analysis Approach Based on Age of Onset, Clinical and Psychopathological Features

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This study investigates clinical heterogeneity in patients with binge eating disorder (BED) and its association with treatment outcomes. Methods A two‐step cluster analysis was conducted on a clinical sample of 196 BED patients, using an agglomerative hierarchical procedure based on both categorical and quantitative measures ...
Lucía Camacho‐Barcia, Lia T. Sánchez‐Salido, Jessica Jiménez del Toro, Roser Granero, Isabel Sánchez, Kim Supit, Nadia Micali, Katrin Elisabeth Giel, Susana Jiménez‐Murcia, Stephan Zipfel, Fernando Fernández‐Aranda   +10 more
wiley   +1 more source

History of Suicidality and Pandemic Outcomes: Longitudinal Associations with Anxiety Symptoms, Depressive Symptoms, and Problematic Drinking

Psychiatric Research and Clinical Practice
Objective Individuals with a history of suicidality may be especially vulnerable to the adverse impact of COVID‐related stressors, but this vulnerability has not been demonstrated.
Jeremy W. Luk, Matthew F. Thompson, Laura A. Novak, Bethany L. Stangl, Melanie L. Schwandt, David Goldman, Vijay A. Ramchandani, Nancy Diazgranados   +7 more
doaj   +1 more source