Results 1 to 10 of about 135 (134)
Aldehyde dehydrogenase in tobacco pollen [PDF]
Plant molecular biology, 1997 Acetaldehyde is one of the intermediate products of ethanolic fermentation, which can be reduced to ethanol by alcohol dehydrogenase (ADH). Alternatively, acetaldehyde can be oxidized to acetate by aldehyde dehydrogenase (ALDH) and subsequently converted to acetyl-CoA by acetyl-CoA synthetase (ACS).
op den Camp, Roel, Kuhlemeier*, Cris
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Aldehyde dehydrogenases and cell proliferation [PDF]
Free Radical Biology and Medicine, 2012 Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or aromatic molecules that play an important role in numerous physiological, pathological, and pharmacological processes.
MUZIO, Giuliana +4 more
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Alcohol dehydrogenase and aldehyde dehydrogenase in malignant neoplasms [PDF]
Clinical and Experimental Medicine, 2016 According to International Agency for Research on Cancer, ethanol and acetaldehyde belong to group 1 of human carcinogens. The accurate mechanism by which alcohol consumption enhances carcinogenesis is still unexplained. Alcohol is oxidized primarily by alcohol dehydrogenase (ADH) to acetaldehyde, a substance capable of initiating carcinogenesis by ...
Maciej Szmitkowski, Karolina Orywal
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Aldehyde dehydrogenase 2 and arrhythmogenesis
Heart Rhythm, 2022 Cardiac arrhythmia is a common cardiovascular disease that leads to considerable economic burdens and significant global public health challenges. Despite the remarkable progress made in recent decades, antiarrhythmic therapy remains suboptimal. Aldehyde dehydrogenase 2 (ALDH2), a critical detoxifying enzyme, catalyzes toxic aldehydes and protects ...
Junyan, Jin, Jieying, Chen, Yaping, Wang
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Soluble aldehyde dehydrogenase and metabolism of aldehydes by soybean bacteroids [PDF]
Journal of Bacteriology, 1982 A soluble aldehyde dehydrogenase (EC 1.2.1.3) was partially purified from Rhizobium japonicum bacteroids and from free-living R. japonicum 61A76. The enzyme was activated by NAD+, NADH, and dithiothreitol, and it reduced NAD(P)+. Acetaldehyde, propionaldehyde, butyraldehyde, benzaldehyde, and succinic semialdehyde were substrates.
T A LaRue, J B Peterson
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Regional localization of the human genes for aldehyde dehydrogenase-1 and aldehyde dehydrogenase-2
Genomics, 1988 We have used the cDNA probes for human aldehyde dehydrogenase-1 (ALDH1) and aldehyde dehydrogenase-2 (ALDH2) to determine regional chromosomal locations of these two genes by in situ hybridization. Results presented here allow localization of ALDH1 to band q21 on chromosome 9 and ALDH2 to band q24 on chromosome 12.
Lily C. Hsu +5 more
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SAXS fingerprints of aldehyde dehydrogenase oligomers
Data in Brief, 2015 Enzymes of the aldehyde dehydrogenase (ALDH) superfamily catalyze the nicotinamide adenine dinucleotide-dependent oxidation of aldehydes to carboxylic acids. ALDHs are important in detoxification of aldehydes, amino acid metabolism, embryogenesis and development, neurotransmission, oxidative stress, and cancer.
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Aldehyde dehydrogenase in human blood [PDF]
FEBS Letters, 1978 Robert C. Vallari, Regina Pietruszko
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THE OXIDATION OF BETAINE ALDEHYDE BY BETAINE ALDEHYDE DEHYDROGENASE
Journal of Biological Chemistry, 1954 E S G Barron, H.A. Rothschild
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ALCOHOL AND ALDEHYDE DEHYDROGENASE* [PDF]
Alcohol and Alcoholism, 1990 The enzymes mainly responsible for ethanol degradation in humans are liver alcohol dehydrogenases (ADH) and aldehyde dehydrogenases (ALDH). Polymorphisms occur in both enzymes, with marked differences in the steady-state kinetic constants. The Km-values for ethanol of ADH isoenzymes relevant for alcohol degradation range from 49 microM to 36 microM ...
William F. Bosron +2 more
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