Results 1 to 10 of about 9,602 (174)

Characterization of human oxidoreductases involved in aldehyde odorant metabolism

Scientific Reports, 2023
Oxidoreductases are major enzymes of xenobiotic metabolism. Consequently, they are essential in the chemoprotection of the human body. Many xenobiotic metabolism enzymes have been shown to be involved in chemosensory tissue protection.
Valentin Boichot, Franck Menetrier, Jean-Michel Saliou, Frederic Lirussi, Francis Canon, Mireille Folia, Jean-Marie Heydel, Thomas Hummel, Susanne Menzel, Maria Steinke, Stephan Hackenberg, Mathieu Schwartz, Fabrice Neiers   +12 more
doaj   +7 more sources

Minimal aromatic aldehyde reduction (MARE) yeast platform for engineering vanillin production [PDF]

Biotechnology for Biofuels and Bioproducts
Background Vanillin represents one of the most widely used flavoring agents in the world. However, microbial synthesis of vanillin is hindered by the host native metabolism that could rapidly degrade vanillin to the byproducts.
Qiwen Mo, Jifeng Yuan
doaj   +2 more sources

Continuous-wave electron paramagnetic resonance (CW-EPR) for studying structure-function relationships in a Cu-containing nitrite reductase and a Mo-containing aldehyde oxidoreductase

Journal of Magnetic Resonance Open, 2023
Transition metal ion-containing oxidoreductases, which carry out long-distance electron transfer reactions, are a large family of metalloproteins that are widely distributed in nature.
Pablo J. González, María G. Rivas, Ana L. Pérez, Carlos D. Brondino   +3 more
doaj   +1 more source

Core and auxiliary functions of one-carbon metabolism in Pseudomonas putida exposed by a systems-level analysis of transcriptional and physiological responses

mSystems, 2023
The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (C1) compounds
Justine Turlin, Òscar Puiggené, Stefano Donati, Nicolas T. Wirth, Pablo I. Nikel   +4 more
doaj   +1 more source

Electrocatalytic Aldehyde Oxidation by a Tungsten Dependent Aldehyde Oxidoreductase from Aromatoleum Aromaticum

Chemistry – A European Journal, 2023
AbstractIn contrast to their molybdenum dependent relatives, tungsten enzymes operate at significantly lower redox potentials, and in some cases they can carry out reversible redox transformations of their substrates and products. Still, the electrochemical properties of W enzymes have received much less attention than their Mo relatives.
Palraj Kalimuthu, Dominik Hege, Agnieszka Winiarska, Yvonne Gemmecker, Maciej Szaleniec, Johann Heider, Paul V. Bernhardt   +6 more
openaire   +2 more sources

Physiological and Molecular Characterization of Yeast Cultures Pre-Adapted for Fermentation of Lignocellulosic Hydrolysate

Fermentation, 2023
Economically feasible bioethanol process from lignocellulose requires efficient fermentation by yeast of all sugars present in the hydrolysate. However, when exposed to lignocellulosic hydrolysate, Saccharomyces cerevisiae is challenged with a variety of
João R. M. Almeida, Magnus Wiman, Dominik Heer, Daniel P. Brink, Uwe Sauer, Bärbel Hahn-Hägerdal, Gunnar Lidén, Marie F. Gorwa-Grauslund   +7 more
doaj   +1 more source

The role of walnut bZIP genes in explant browning

BMC Genomics, 2023
Background Basic leucine zipper (bZIP) proteins are important transcription factors in plants. To study the role of bZIP transcription factors in walnut explant browning, this study used bioinformatics software to analyze walnut bZIP gene family members,
Hui Wang, Jiali Peng, Yaoling Li, Lishan Xu, Wenqiang Dai, Shugang Zhao   +5 more
doaj   +1 more source

The Metabolism of Clostridium ljungdahlii in Phosphotransacetylase Negative Strains and Development of an Ethanologenic Strain

Frontiers in Bioengineering and Biotechnology, 2020
The sustainable production of chemicals from non-petrochemical sources is one of the greatest challenges of our time. CO2 release from industrial activity is not environmentally friendly yet provides an inexpensive feedstock for chemical production.
Jonathan Lo, Jonathan R. Humphreys, Joshua Jack, Chris Urban, Lauren Magnusson, Wei Xiong, Yang Gu, Zhiyong Jason Ren, Pin-Ching Maness   +8 more
doaj   +1 more source

Experimental Evolution Reveals a Novel Ene Reductase That Detoxifies α,β-Unsaturated Aldehydes in Listeria monocytogenes

Microbiology Spectrum, 2023
The plant essential oil component trans-cinnamaldehyde (t-CIN) exhibits antibacterial activity against a broad range of foodborne pathogenic bacteria, including L. monocytogenes, but its mode of action is not fully understood.
Lei Sun, Ann Van Loey, Carolien Buvé, Chris W. Michiels   +3 more
doaj   +1 more source

Reductive enzymatic dynamic kinetic resolution affording 115 g/L (S)-2-phenylpropanol

BMC Biotechnology, 2021
Background Published biocatalytic routes for accessing enantiopure 2-phenylpropanol using oxidoreductases afforded maximal product titers of only 80 mM. Enzyme deactivation was identified as the major limitation and was attributed to adduct formation of ...
Christian Rapp, Simone Pival-Marko, Erika Tassano, Bernd Nidetzky, Regina Kratzer   +4 more
doaj   +1 more source