Results 51 to 60 of about 8,399 (179)

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Sulfite: Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidoreductase from \u3cem\u3eThiobacillus novellus\u3c/em\u3e [PDF]

, 2000
Direct oxidation of sulfite to sulfate occurs in various photo- and chemotrophic sulfur oxidizing microorganisms as the final step in the oxidation of reduced sulfur compounds and is catalyzed by sulfite:cytochrome c oxidoreductase (EC1.8.2.1).
Bennett, Brian, Dahl, Christiane, Deutzmann, Rainer, Kappler, Ulrike, McEwan, Alistair G., Rethmeier, Jörg, Schwarz, Günter   +6 more
core   +1 more source

A Genome‐Wide Association Screen for Genes Affecting Leaf Trichome Development and Epidermal Metal Accumulation in Arabidopsis

Plant, Cell &Environment, Volume 48, Issue 5, Page 3708-3734, May 2025.
ABSTRACT To identify novel genes engaged in plant epidermal development, we characterized the phenotypic variability of rosette leaf epidermis of 310 sequenced Arabidopsis thaliana accessions, focusing on trichome shape and distribution, compositional characteristics of the trichome cell wall, and histologically detectable metal ion distribution.
Radek Bezvoda, Yazmín Mónica Landeo‐Ríos, Zdeňka Kubátová, Eva Kollárová, Ivan Kulich, Wolfgang Busch, Viktor Žárský, Fatima Cvrčková   +7 more
wiley   +1 more source

Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4-hydroxynonenal [PDF]

Biochemical Journal, 1998
The aim of this study was to identify the cardiac oxidoreductases involved in the metabolism of 4-hydroxy-2-trans-nonenal (HNE), an α,β unsaturated aldehyde generated during the peroxidation of ω-6 polyunsaturated fatty acids. In homogenates of bovine, human and rat ventricles the primary pyridine coenzyme-linked metabolism of HNE was associated with ...
K. Satish Srivastava, H. Naseem Ansari, Sanjay K. Srivastava, Animesh Chandra, Aruni Bhatnagar   +4 more
openaire   +3 more sources

Effects of hydroxycinnamic acids on the glycolysis pathway [PDF]

, 2019
Glycolysis is a metabolic pathway vital to the production of energy and some organisms rely on it solely to meet their energy requirements. It is also a central pathway in the metabolism of carbohydrates and a source of therapeutic targets against ...
Castilho, P. C., Fernandes, M. X., Serina, J.   +2 more
core   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Transcriptomic analysis of the mandibular gland genes associated with reproductive dominance in Apis mellifera capensis Esch. parasitic workers

Physiological Entomology, EarlyView.
Biosynthesis of the fatty acid components of the Apis mellifera mandibular gland pheromones takes place in a stepwise manner. Differential gene expression in the mandibular gland tissue of workers from two subspecies of African honey bees with differing reproductive potentials and at two age groups was investigated.
Fiona Nelima Mumoki, Christian Walter Werner Pirk, Robin Michael Crewe, Abdullahi Ahmed Yusuf   +3 more
wiley   +1 more source

Genetic changes that increase 5-hydroxymethyl furfural resistance in ethanol-producing Escherichia coli LY180 [PDF]

, 2010
The ability of a biocatalyst to tolerate furan inhibitors present in hemicellulose hydrolysates is important for the production of renewable chemicals. This study shows EMFR9, a furfural-tolerant mutant of ethanologenic E.
A Martinez, A Martinez, A Martinez, BH Um, CE Wyman, E Palmqvist, E Palmqvist, E. N. Miller, EN Miller, EN Miller, IM Keseler, J Zaldivar, JE Purvis, JRM Almeida, JRM Almeida, KK Cheng, L. O. Ingram, L. R. Jarboe, MJ Taherzadeh, P. C. Turner, R Boopathy, SW Gorsich, ZL Liu   +22 more
core   +2 more sources

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen, Huanle Qi, Yapeng Xue, Yaqi Zhang, Zhuo Zhang, Shun Xu, Shixin Liao, Xiaoyu Zeng, Jiayi Wu, Xinrui Lv, Qiankun He, Pingping Zhu   +11 more
wiley   +1 more source

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, Volume 45, Issue 3, Page 177-201, June 2025.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source