Results 171 to 180 of about 232,884 (341)

Cardiometabolic outcomes with dapagliflozin after myocardial infarction by baseline ejection fraction: DAPA‐MI

open access: yesESC Heart Failure, EarlyView.
We investigated cardiometabolic outcomes in patients treated with dapagliflozin 10 mg once daily or placebo after acute myocardial infarction according to LVEF at randomisation in the registry‐based, randomised DAPA‐MI trial. Regardless of baseline LVEF, dapagliflozin resulted in significant cardiometabolic benefits versus placebo, suggesting that ...
David Erlinge   +19 more
wiley   +1 more source

Soluble urokinase plasminogen activator receptor and outcomes in HFpEF: A TOPCAT ancillary study

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Inflammation is postulated to be a key pathogenic mechanism in heart failure with preserved ejection fraction (HFpEF). Soluble urokinase plasminogen activator receptor (suPAR), a regulator of innate immune activity, is associated with incident heart failure; however, its role in HFpEF remains unclear.
Christina G. Hutten   +9 more
wiley   +1 more source

The prognostic value of the Dandel's index in patients undergoing tricuspid transcatheter edge‐to‐edge repair

open access: yesEuropean Journal of Heart Failure, EarlyView.
Load adaptation indices and concepts. An adapted RV in response to overload increases wall thickness to normalize wall stress and preserve function and morphology. If hemodynamic overload is sustained, it can progress to a maladaptive state and lead eventually to heart failure. CI, cardiac index; Ees, ventricular elastance; Ea, arterial elastance; MPAP,
Mohammad Kassar   +39 more
wiley   +1 more source

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

open access: yesEuropean Journal of Heart Failure, EarlyView.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo   +11 more
wiley   +1 more source

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