Results 21 to 30 of about 106,036 (288)
Frontiers in Physiology, 2022 Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na+ reabsorption via the epithelial Na+ channel (ENaC) and the NaCl cotransporter (NCC).
Mathias Kristensen +2 more
doaj +1 more source
Physiological Reports, 2021 Restricting dietary sodium promotes sodium appetite in rats. Prolonged sodium restriction increases plasma potassium (pK), and elevated pK is largely responsible for a concurrent increase in aldosterone, which helps promote sodium appetite.
Frederico S. Fazan +3 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ObjectiveTo examine the consistency of plasma aldosterone concentration at 1 and 2 h in the captopril challenge test (CCT) and to explore the possibility of replacing 2-h aldosterone concentration with 1-h aldosterone concentration for diagnosis of ...
Xinyu Liu +8 more
doaj +1 more source
Gland Surgery, 2020 Primary aldosteronism (PA) is a common cause of secondary hypertension caused by excessive and inappropriate secretion of the hormone aldosterone from one or both adrenal glands. The prevalence of PA ranges from 10% in the general hypertensive population to 20% in resistant hypertension, yet only a small fraction of patients is diagnosed.
Sean M, Wrenn +2 more
openaire +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
PLoS ONE, 2014 Prolonged elevations of plasma aldosterone levels are associated with renal pathogenesis. We hypothesized that renal distress could be imposed by an augmented aldosterone-induced protein turnover challenging cellular protein degradation systems of the ...
Muhammad Umar Cheema +6 more
doaj +1 more source
Indicators of humoral regulation of the circulatory system in obese patients [PDF]
Наука и инновации в медицине, 2020 Objectives to study the indicators of humoral regulation of circulatory system in obese patients as the predictors of CHF development. Materials and methods.Two groups of 40 patients were formed: the first group consisted of patients with I or II ...
Tatyana S. Zaletova +3 more
doaj +1 more source
Journal of Pharmacological Sciences, 2008 There is increasing evidence indicating the roles of aldosterone and mineralocorticoid receptor (MR) in the pathogenesis of renal injury. In rats, chronic treatment with aldosterone and salt results in severe proteinuria and renal tissue injury ...
Hideyasu Kiyomoto +3 more
doaj +1 more source
THE GENDER FEATURES OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN HYPERTENSIVE PATIENTS
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study the correlation of the renin-angiotensin-aldosterone system (RAAS) activity with the female sex hormone levels and markers of target organ damage in patients with arterial hypertension (HT).Material and methods. Patients with HT (20 men and
V. I. Podzolkov +3 more
doaj +1 more source
Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source