Results 21 to 30 of about 84,187 (148)
Frontiers in Endocrinology, 2021 Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension. It can be caused by the overproduction of aldosterone in one or both adrenal glands. The most common subtypes of PA are unilateral aldosterone over-production
Fatin Athirah Pauzi, Elena Aisha Azizan
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Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. [PDF]
PLoS ONE, 2014 Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis.To investigate whether aldosterone induces galectin-3 secretion
Yen-Hung Lin +11 more
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Frontiers in Physiology, 2022 Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na+ reabsorption via the epithelial Na+ channel (ENaC) and the NaCl cotransporter (NCC).
Mathias Kristensen +2 more
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Biomedicines, 2021 Aldosterone excess plays a major role in the progression of cardiac dysfunction and remodeling in clinical diseases such as primary aldosteronism and heart failure. However, the effect of aldosterone excess on cardiac mitochondria is unclear.
Cheng-Hsuan Tsai +12 more
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Aldosterone, Inflammation, Immune System, and Hypertension
American Journal of Hypertension, 2020 Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance. Excess aldosterone is associated with cardiovascular and metabolic diseases.
N. Ferreira +3 more
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Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma
HYPERTENSION, 2020 Supplemental Digital Content is available in the text. Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent form of secondary hypertension.
Kelly De Sousa +12 more
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Body mass index predicts aldosterone production in hypertensive postmenopausal women
Clinical and Experimental Hypertension, 2020 Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic. Related works have shown exciting results on the effects of various conditions on aldosterone content, but the correlation between ...
Lijun Li +3 more
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Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
Kidney Research and Clinical Practice, 2015 Background: Peritoneal fibrosis is one of the major causes of technical failure in patients on peritoneal dialysis. Epithelial-to-mesenchymal transition (EMT) of the peritoneum is an early and reversible mechanism of peritoneal fibrosis. Human peritoneal
Mina Yu +6 more
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Somatic CACNA1H Mutation As a Cause of Aldosterone-Producing Adenoma
HYPERTENSION, 2020 Supplemental Digital Content is available in the text. Driver somatic mutations for aldosterone excess have been found in ≈90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2)-guided sequencing approach.
K. Nanba +10 more
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Relationship between aldosterone and the metabolic syndrome in patients with obstructive sleep apnea hypopnea syndrome: effect of continuous positive airway pressure treatment. [PDF]
PLoS ONE, 2014 BACKGROUND: Metabolic syndrome (MS) occurs frequently in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). We hypothesized that aldosterone levels are elevated in OSAHS and associated with the presence of MS.
Antonia Barceló +9 more
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