Results 21 to 30 of about 232,884 (341)

Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19

New England Journal of Medicine, 2020
Background There is concern about the potential of an increased risk related to medications that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus disease 2019 (Covid-19), because the viral receptor is angiotensin ...
H. Reynolds, S. Adhikari, C. Pulgarin, A. Troxel, E. Iturrate, Stephen B. Johnson, A. Hausvater, J. Newman, J. Berger, S. Bangalore, S. Katz, G. Fishman, Dennis Kunichoff, Yu Chen, G. Ogedegbe, J. Hochman   +15 more
semanticscholar   +1 more source

Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19

New England Journal of Medicine, 2020
Background A potential association between the use of angiotensin-receptor blockers (ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus disease 2019 (Covid-19) has not been well studied.
G. Mancia, F. Rea, M. Ludergnani, G. Apolone, G. Corrao   +4 more
semanticscholar   +1 more source

Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension

Frontiers in Endocrinology, 2021
Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension. It can be caused by the overproduction of aldosterone in one or both adrenal glands. The most common subtypes of PA are unilateral aldosterone over-production
Fatin Athirah Pauzi, Elena Aisha Azizan
doaj   +1 more source

Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. [PDF]

PLoS ONE, 2014
Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis.To investigate whether aldosterone induces galectin-3 secretion
Yen-Hung Lin, Chia-Hung Chou, Xue-Ming Wu, Yi-Yao Chang, Chi-Sheng Hung, Ying-Hsien Chen, Yu-Lin Tzeng, Vin-Cent Wu, Yi-Lwun Ho, Fon-Jou Hsieh, Kwan-Dun Wu, TAIPAI Study Group   +11 more
doaj   +1 more source

Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na+ Channel and the NaCl Cotransporter

Frontiers in Physiology, 2022
Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na+ reabsorption via the epithelial Na+ channel (ENaC) and the NaCl cotransporter (NCC).
Mathias Kristensen, Robert A. Fenton, Søren B. Poulsen   +2 more
doaj   +1 more source

Aldosterone Excess Induced Mitochondria Decrease and Dysfunction via Mineralocorticoid Receptor and Oxidative Stress In Vitro and In Vivo

Biomedicines, 2021
Aldosterone excess plays a major role in the progression of cardiac dysfunction and remodeling in clinical diseases such as primary aldosteronism and heart failure. However, the effect of aldosterone excess on cardiac mitochondria is unclear.
Cheng-Hsuan Tsai, Chien-Ting Pan, Yi-Yao Chang, Shih-Yuan Peng, Po-Chin Lee, Che-Wei Liao, Chia-Tung Shun, Po-Ting Li, Vin-Cent Wu, Chia-Hung Chou, I-Jung Tsai, Chi-Sheng Hung, Yen-Hung Lin   +12 more
doaj   +1 more source

Aldosterone, Inflammation, Immune System, and Hypertension

American Journal of Hypertension, 2020
Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance. Excess aldosterone is associated with cardiovascular and metabolic diseases.
N. Ferreira, R. Tostes, P. Paradis, E. Schiffrin   +3 more
semanticscholar   +1 more source

Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma

HYPERTENSION, 2020
Supplemental Digital Content is available in the text. Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent form of secondary hypertension.
Kelly De Sousa, S. Boulkroun, S. Baron, K. Nanba, M. Wack, W. Rainey, A. Rocha, I. Giscos-Douriez, T. Méatchi, L. Amar, Simon Travers, F. Fernandes-Rosa, M. Zennaro   +12 more
semanticscholar   +1 more source

Body mass index predicts aldosterone production in hypertensive postmenopausal women

Clinical and Experimental Hypertension, 2020
Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic. Related works have shown exciting results on the effects of various conditions on aldosterone content, but the correlation between ...
Lijun Li, Xiaoling Hou, Xiaowen Geng, Yong Xu   +3 more
doaj   +1 more source

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C., Freel, E.M., Latini, R., Lewsey, J.D., Maggioni, A.P., McMurray, J.J.V., Pitt, B., Solomon, S., Tsorlalis, I.K.   +8 more
core   +1 more source