Results 21 to 30 of about 12,436 (107)

The Effect of Vitamin D3 Supplementation on the Risk of Falls in a General Population—The Finnish Vitamin D Trial

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The impact of vitamin D on fall incidence remains controversial. We studied the effect of 5 years of vitamin D3 supplementation on the risk of falls in a double‐blind, placebo‐controlled randomized trial with generally healthy, community‐dwelling men and women in Finland.
Toni Rikkonen, Sari Hantunen, Heikki Kröger, Christel Lamberg‐Allardt, JoAnn E. Manson, Tarja Nurmi, Marjo Tuppurainen, Ari Voutilainen, Tomi‐Pekka Tuomainen, Jyrki K. Virtanen   +9 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

The Application of Metal–Organic Frameworks as Drug Delivery Systems: From the Perspective of Molecular Dynamics Simulations

MedComm, Volume 7, Issue 4, April 2026.
This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu, Hanzi Zheng, Yue Gao, Yuanqiu Lai, Mengya Peng, Yike Hu, Tianmeng Yuan, Xiang Liu, Shihan Zhou, Wei Duan, Jia‐Wei Shen, Yongke Zheng   +11 more
wiley   +1 more source

Interventions for the Diagnosis and Management of Otosclerosis: An Umbrella Review

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 4, Page 904-915, April 2026.
Abstract Objective Perform an umbrella review (a systematic review of systematic reviews) to identify interventions for the prevention, diagnosis, and management of otosclerosis, to inform the development of the World Health Organization (WHO) Package of Ear and Hearing Care Interventions (PEHCI). Data Sources PubMed, Scopus, and Ovid MEDLINE databases
Isabelle J. Chau, Lauren R. McCray, Shaun A. Nguyen, Robert F. Labadie, Carolina Der, Lauren K. Dillard   +5 more
wiley   +1 more source

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, Volume 104, Issue 4, Page 302-311, April 2026.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source

Development of Tunable Materials From Well‐Defined Alendronic Acid Functionalized Polyacrylamide: An Opportunity for Actinide Decontamination

Journal of Polymer Science, Volume 64, Issue 6, Page 1431-1443, 15 March 2026.
Alendronate‐based copolymers for Nd and Ce recovery. ABSTRACT Bisphosphonic acid groups are emerging as promising functionalities for actinide decontamination, due to their high density of chelating sites. However, the chemistry of bisphosphonate (in particular alendronate) materials remains complex and underexplored.
Vincent Darcos, Loona Ferrie, Carlos Arrambide, Gabriele Vecchio, Nicolas Dacheux, Stephane Pellet‐Rostaing, Benedicte Prelot, Sophie Monge   +7 more
wiley   +1 more source

A network meta-analysis of randomized controlled trials evaluating the evidence of pharmacological agents and growth factors in the regeneration of bony defects in chronic periodontitis. [PDF]

BMC Oral Health
Koli S, Rathod S, Kolte A, Jaiswal P, Kotecha S.   +4 more
europepmc   +1 more source