Expression, Purification, and Characterisation of Recombinant Alginate Lyase (Flammeovirga AL2) for the Bioconversion of Alginate into Alginate Oligosaccharides [PDF]
MoleculesAlginate, a polysaccharide found in brown seaweeds, has regularly gained attention for its potential use as a source of bioactive compounds. However, it is structurally complex with a high molecular weight, limiting its application.
Coleen E. Grobler +4 more
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Alginate oligosaccharides can maintain activities of lysosomes under low pH condition [PDF]
Scientific Reports, 2021 The objective of this study was to report that lysosome extracted from egg white could be used as a drug through oral administration for treating diseases by using pH sensitive alginate oligosaccharides.
Ra-Mi Park +4 more
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Production of Alginate Oligosaccharides (AOSs) Using Enhanced Physicochemical Properties of Immobilized Alginate Lyase for Industrial Application [PDF]
Marine DrugsAlginate lyase (AL) is a polysaccharide-degrading enzyme that can degrade alginate by hydrolyzing glycosidic bonds and produces unsaturated alginate oligosaccharides (AOSs). These AOSs have wide therapeutic and nutraceutical applications.
Simranjeet Kaur +3 more
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Alginate Oligosaccharides Prevent Dextran-Sulfate-Sodium-Induced Ulcerative Colitis via Enhancing Intestinal Barrier Function and Modulating Gut Microbiota [PDF]
Foods, 2023 Alginate oligosaccharides are degradation products of alginate and have attracted increasing attention due to their versatile biological functions.
Axue Wu +6 more
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Identification and Characterization of a New Cold-Adapted and Alkaline Alginate Lyase TsAly7A from Thalassomonas sp. LD5 Produces Alginate Oligosaccharides with High Degree of Polymerization [PDF]
Marine Drugs, 2022 Alginate oligosaccharides (AOS) and their derivatives become popular due to their favorable biological activity, and the key to producing functional AOS is to find efficient alginate lyases.
Chengying Yin +4 more
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Review on Preparation, Separation and Characterization of Alginate Oligosaccharide
Shipin gongye ke-ji, 2022 Alginate oligosaccharide (AOS) is a kind of low molecular polymer, which is composed of 2~25 monosaccharides (mannuronic acidandguluronic acid) by glycoside bond.
Yiqing LIU +6 more
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Elucidation of degrading pattern and substrate recognition of a novel bifunctional alginate lyase from Flammeovirga sp. NJ-04 and its use for preparation alginate oligosaccharides [PDF]
Biotechnology for Biofuels, 2019 Background The alginate oligosaccharides have been widely used in agriculture, medicine, and food industries due to their versatile physiological functions such as antioxidant, anticoagulant, and antineoplastic activities.
Benwei Zhu +4 more
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Genome Analysis of a Potential Novel Vibrio Species Secreting pH- and Thermo-Stable Alginate Lyase and Its Application in Producing Alginate Oligosaccharides [PDF]
Marine DrugsAlginate lyase is an attractive biocatalyst that can specifically degrade alginate to produce oligosaccharides, showing great potential for industrial and medicinal applications.
Ke Bao +4 more
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Effects of two kinds of marine algae polysaccharides and their oligosaccharides on lipid metabolism and gut microbiota in high-fat diet mice [PDF]
Microbiology SpectrumAbnormal lipid metabolism is manifested in a variety of metabolic diseases. In recent years, studies have shown that the pathogenesis of these disorders is closely associated with the gut microbiota.
Zi-ang Yao, Ling Xu, Yu Liu, Hai-ge Wu
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Marine Drugs, 2023 Alginate oligosaccharides prepared by alginate lyases attracted great attention because of their desirable biological activities. However, the hydrolysis products are always a mixture of oligosaccharides with different degrees of polymerization, which ...
Zhiqiang Shu +7 more
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