Enzymatic Hydrolysis of Alginate to Produce Oligosaccharides by a New Purified Endo-Type Alginate Lyase [PDF]
Marine Drugs, 2016 Enzymatic hydrolysis of sodium alginate to produce alginate oligosaccharides has drawn increasing attention due to its advantages of containing a wild reaction condition, excellent gel properties and specific products easy for purification.
Benwei Zhu +4 more
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A Recombinant Alginate Lyase Algt1 with Potential in Preparing Alginate Oligosaccharides at High-Concentration Substrate. [PDF]
Foods, 2023 Alginate lyase has been demonstrated as an efficient tool in the preparation of functional oligosaccharides (AOS) from alginate. The high viscosity resulting from the high concentration of alginate poses a limiting factor affecting enzymatic hydrolysis, particularly in the preparation of the fragments with low degrees of polymerization (DP).
Liang Q +9 more
europepmc +4 more sources
A Novel Cold-Adapted and High-Alkaline Alginate Lyase with Potential for Alginate Oligosaccharides Preparation. [PDF]
Molecules, 2023 Alginate oligosaccharides (AOs) prepared through enzymatic reaction by diverse alginate lyases under relatively controllable and moderate conditions possess versatile biological activities. But widely used commercial alginate lyases are still rather rare due to their poor properties (e.g., lower activity, worse thermostability, ion tolerance, etc.). In
Wang HY +5 more
europepmc +4 more sources
Advances in Research on the Bioactivity of Alginate Oligosaccharides. [PDF]
Mar Drugs, 2020 Alginate is a natural polysaccharide present in various marine brown seaweeds. Alginate oligosaccharide (AOS) is a degradation product of alginate, which has received increasing attention due to its low molecular weight and promising biological activity. The wide-ranging biological activity of AOS is closely related to the diversity of their structures.
Xing M +7 more
europepmc +5 more sources
Synthesis of Alginate Oligosaccharide (AOS) Using Different Solvents [PDF]
Indonesian Journal of Biotechnology and Biodiversity, 2021 Alginate oligosaccharide (AOS) is an oligosaccharide synthesized by depolymerizing alginate and has various industrial applications. This research determines the best solvent and the optimal concentration of the best solvent to produce AOS. Peroxides and hydrochloric acid can be used[L1] as solvents, but the residue might cause some danger if the AOS ...
Nathaniel Nainggolan +2 more
openaire +1 more source
Detection of Alginate Oligosaccharides from Mollusks [PDF]
Bioscience, Biotechnology, and Biochemistry, 2006 We attempted in this study to detect alginate oligosaccharides (AO) from mollusks. The samples used were digestive organs taken from turban shells and abalones which commonly ate brown algae. High-performance liquid chromatography (HPLC) and negative-ion electrospray ionization (ESI) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) analyses ...
Takamitsu, Chaki +3 more
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Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms. [PDF]
Front Cell Infect Microbiol, 2023 BackgroundThe increasing prevalence of invasive fungal infections in immuno-compromised patients is a considerable cause of morbidity and mortality. With the rapid emergence of antifungal resistance and an inadequate pipeline of new therapies, novel treatment strategies are now urgently required.MethodsThe antifungal activity of the alginate ...
Powell LC +12 more
europepmc +6 more sources
Expression and Characterization of an Alginate Lyase and Its Thermostable Mutant in Pichia pastoris
Marine Drugs, 2020 Alginate is one of the most abundant polysaccharides in algae. Alginate lyase degrades alginate through a β-elimination mechanism to produce alginate oligosaccharides with special bioactivities. Improving enzyme activity and thermal stability can promote
Suxiao Yang +6 more
doaj +1 more source
Research Progress on Preparation of Marine Oligosaccharides by Enzymatic Method
Shipin gongye ke-ji, 2023 Marine oligosaccharides, which are prepared by degradation of marine polysaccharides, are carbohydrate compounds composed of two to ten monosaccharide residues.
Zixiang YANG +9 more
doaj +1 more source
Alginate Oligosaccharides Affect Mechanical Properties and Antifungal Activity of Alginate Buccal Films with Posaconazole. [PDF]
Mar Drugs, 2019 Sodium alginate and its oligosaccharides through potential antifungal properties might improve the activity of antifungal drugs enhancing their efficacy and potentially reducing the frequency of application. Mucoadhesive buccal films are oral dosage forms designed for maintaining both local or systemic drug effects and seem to be a very promising ...
Szekalska M +4 more
europepmc +5 more sources