Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)
, 2020 Alkaloids are a large cluster of molecules found in Mother Nature all over the world. They are all secondary compounds and collection of miscellaneous elements and biomolecules, derived from amino acids or from transamination. This diverse chemical group is categorized, based on the amino acids that deliver their nitrogen atom and part of their ...
Dey, Prasanta +7 more
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Workflow for investigation of Out of Specification results in physico-chemical laboratory in Alkaloid [PDF]
Makedonsko Farmacevtski BiltenThe efficient and accurate investigation of Out of Specification (OOS) results is crucial in maintaining the reliability and quality of products in a physico-chemical laboratory.
Andrea Alagjozovska +8 more
doaj +1 more source
Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]
, 2008 Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T. +5 more
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Preformulation Characterization of Hydroxypropyl Cellulose Microparticles for Drug Delivery Applications: A Basis for Rational Design and Process Optimization [PDF]
Chemical and Biochemical Engineering QuarterlyThis study explores early formulation parameters influencing hydroxypropyl cellulose (HPC)-based microparticles as carriers for paracetamol, with the aim of establishing a modified-release drug delivery system and informing future design optimization ...
T. Georgievska +4 more
doaj +1 more source
Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]
, 2014 Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain +11 more
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How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]
, 2014 The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
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Advantages of trend analysis in stability studies for prediction of potential OOS result within estimated shelflife of medicinal product [PDF]
Makedonsko Farmacevtski BiltenStability studies are crucial for pharmaceutical product registration, providing vital data to assess batch-to-batch consistency, monitor critical quality attributes, and ensure the product's quality, safety, and efficacy over its entire shelf life ...
Milena Nanov +4 more
doaj +1 more source
Optimization of a forced degradation study of atorvastatin employing an experimental design approach
Macedonian Journal of Chemistry and Chemical Engineering, 2018 This study involved the optimization of experimental conditions for the forced degradation of atorvastatin employing the experimental design (DoE) approach, as a scientific multifactorial strategy.
Maja Hadzieva Gigovska +7 more
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Advancements in lead therapeutic phytochemicals polycystic ovary syndrome: A review
Frontiers in Pharmacology, 2023 Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women of reproductive age and features complex pathological symptoms and mechanisms.
Er-Dan Luo +10 more
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Influence of different formulations and granulation techniques on dissolution of folic acid in film coated tablets [PDF]
Makedonsko Farmacevtski Bilten, 2011 The vitamin folic acid has received considerable attention because of it′s role in decreasing risk of neural tube birth defects, and it′s potential role in reducing risks of cardiovascular and psychiatric diseases.
Ljiljana Krsteska +4 more
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