Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]
, 2011 The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena +5 more
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Influence of different formulations and granulation techniques on dissolution of folic acid in film coated tablets [PDF]
Makedonsko Farmacevtski Bilten, 2011 The vitamin folic acid has received considerable attention because of it′s role in decreasing risk of neural tube birth defects, and it′s potential role in reducing risks of cardiovascular and psychiatric diseases.
Ljiljana Krsteska +4 more
doaj
Fast and selective HPLC-DAD method for determination of pholcodine and related substances
Macedonian Journal of Chemistry and Chemical Engineering, 2011 Quality control of pharmaceuticals requires development of fast, efficient and reliable methods for determination of active compounds as well as known and very often unknown impurities within defined concentration ranges. In this work, a simple and rapid
Ana Petkovska +2 more
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Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]
, 2008 Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T. +5 more
core +2 more sources
Pharmaceuticals, 2023 Cervical cancer is the fourth-most common type of cancer in the world that causes death in women. It is mainly caused by persistent infection by human papillomavirus (HPV) that triggers a chronic inflammatory process.
Luana Pereira Cardoso +8 more
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7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]
, 2019 Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael +12 more
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Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
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Network-analysis-guided synthesis of weisaconitine D and liljestrandinine. [PDF]
, 2015 General strategies for the chemical synthesis of organic compounds, especially of architecturally complex natural products, are not easily identified. Here we present a method to establish a strategy for such syntheses, which uses network analysis.
Gallego, GM +8 more
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Validacija na metod za opredeluvanje mikrobioloska cistota na Kafetin® tableti [PDF]
Makedonsko Farmacevtski Bilten, 2003 Izvrsena e validacija na metodot za opredeluvawe mikrobioloska cistota na Kafetin® tableti. Za taa cel koristeni se test-mikroorganizmi: Escherichia coli, Pseudomonas aeruginosa ,Staphylococcus aureus, Candida albicans i Aspergillus niger, od ...
Dragi Todorovik +2 more
doaj
Analytical Quality by Design approach in development and optimization of HPLC method for assay of angiotensin – converting enzyme inhibitor in tablets [PDF]
Makedonsko Farmacevtski BiltenImplementation of analytical quality by design approach is a helpful tool in development of a robust analytical method which is applicable throughout the lifecycle of the product.
Veronika Popovska Jakimovska +7 more
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