Results 31 to 40 of about 229,143 (305)
Analytical Quality by Design approach in development and optimization of HPLC method for assay of angiotensin – converting enzyme inhibitor in tablets [PDF]
Makedonsko Farmacevtski BiltenImplementation of analytical quality by design approach is a helpful tool in development of a robust analytical method which is applicable throughout the lifecycle of the product.
Veronika Popovska Jakimovska +7 more
doaj +1 more source
Marine Organisms as Alkaloid Biosynthesizers of Potential Anti-Alzheimer Agents
Marine Drugs, 2022 The incidence of neurodegenerative diseases, such as Alzheimer’s disease (AD), increases continuously demanding the urgent development of anti-Alzheimer’s agents.
Elisabete Lima, Jorge Medeiros
doaj +1 more source
Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
core +1 more source
Journal of Analytical Methods in Chemistry, 2019 The purpose of this study was to develop and validate a discriminative dissolution method for the metformin film-coated tablet with immediate release of the active substance that belongs to class III of the Biopharmaceutical Classification System (BCS ...
Ivana Mitrevska +5 more
doaj +1 more source
, 2017 Cephalotaxus alkaloids represent a family of plant secondary metabolites known for 60 years. Significant activity against leukemia in mice was demonstrated for extracts of Cephalotaxus. Cephalotaxine (CET) (1), the major alkaloid of this series was isolated from Cephalotaxus drupacea species by Paudler in 1963.
Pérard-Viret, Joelle +4 more
openaire +3 more sources
Optimized genotyping method for identification of bacterial contaminants in pharmaceutical industry
Acta Pharmaceutica, 2016 Microbiological control is of crucial importance in the pharmaceutical industry regarding the possible bacterial contamination of the environment, water, raw materials and finished products. Molecular identification of bacterial contaminants based on DNA
Stamatoski Borche +4 more
doaj +1 more source
Nat. Prod. Rep., 2014 This review focuses on the isolation and synthesis of natural products containing a 1-azabicyclo[3.3.0]octane core (July 2001 to December 2012).
Robertson, J, Stevens, K
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
International Journal of Analytical Chemistry, 2018 This manuscript describes comprehensive approach for assessment of degradation behavior of simvastatin employing experimental design methodology as scientific multifactorial strategy.
Maja Hadzieva Gigovska +6 more
doaj +1 more source
Macedonian Journal of Chemistry and Chemical Engineering, 2015 Thebaine is naturally occurring alkaloid which is of great importance in the pharmaceutical industry and up to now there is not a Pharmacopoeial monograph for this compound.
Marija Spasevska +2 more
doaj +1 more source