The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde +4 more
wiley +1 more source
Chemical Constituents, Pharmacological Activities, and Cardiovascular Protective Mechanisms of <i>Dendrobium</i> Species: A Review. [PDF]
Hu Y, Li Z, Li J, Li X, Wang M.
europepmc +1 more source
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone +5 more
wiley +1 more source
Avoiding False Identification of 7-Hydroxymitragynine in Kratom Products Using a Multicriteria LC-MS Confirmation. [PDF]
Sheehan D +4 more
europepmc +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Molecular docking and experimental evaluation of natural alkaloids from Chilean flora (<i>Cryptocarya alba</i>, <i>Peumus boldus</i>, and <i>Laurelia sempervirens</i>) for tyrosinase inhibition and depigmenting potential. [PDF]
Castro-Saavedra S +3 more
europepmc +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
In Silico and In Vitro Evaluation of Bioactive Constituents Isolated from <i>Ziziphus oxyphylla</i> for the Treatment of Diabetes. [PDF]
Zia-Ul-Haq M +6 more
europepmc +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Bioactivity-guided metabolomics reveals discriminant cytotoxic signatures in Siparuna guianensis. [PDF]
Asghar S +10 more
europepmc +1 more source

