Results 181 to 190 of about 184,232 (306)

Alkaloids as Emerging Neuroprotective Agents for Neurodegenerative Disorders: Insights into Tryptanthrin and Its Derivatives. [PDF]

Int J Mol Sci
Khan A, Khan H, Park IH, Aldahmash BA, Khan MS, Yang G, Kang KS.   +6 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Revisiting the leaf anatomy of Hymenaea martiana: new insights from anatomical and histochemical techniques

Nordic Journal of Botany, EarlyView.
Hymenaea martiana, known as ‘jatobá', is used in folk medicine and has similarities with Hymenaea courbaril, making its recognition difficult. Although there are different pharmacological reports that attest to its bioactive potential, there are few studies with leaf extracts in H. martiana.
Catarina Silva Lima, João Victor da Costa Santos, João Gilberto Meza Ucella Filho, Josiane Silva Araújo   +3 more
wiley   +1 more source

Chemical diversity and phylogenetic insights into Hawaiian ʻākia (Wikstroemia) species used in traditional fishing practices

PLANTS, PEOPLE, PLANET, EarlyView.
Traditional fishing with plant‐based piscicides is a global practice in decline, facing increasing restrictions. We investigated the chemical diversity of endemic Wikstroemia species historically used to stun or poison fish in Hawaiʻi. Using 1‐H‐NMR, principal component analysis, targeted HPLC, and target‐capture sequencing, we characterized compounds ...
Louise Winther, Isaac Lichter‐Marck, Louise Kjaerulff, David Lorence, Uma Nagendra, Mike Opgenorth, Sverre J. Schou, Kenneth R. Wood, Felipe Zapata, Dan Staerk, Nina Rønsted   +10 more
wiley   +1 more source

Building a genomic and herbarium biorepository for medicinal plants of the Western Ghats

PLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants support healthcare for millions of people and sustain livelihoods, yet many threatened species lack secure long‐term genetic protection. This study establishes a genomic and herbarium biorepository for medicinal plants of the Western Ghats, a global biodiversity hotspot facing intense human pressure.
Anurag Dhyani, Mathew Dan, Kalluvettankuzhy Krishnannair Sabu, Maniyannair Pankajakshiamma Geethakumary, Muhammed Abdul Jabbar, Sivankunju Suresh, Morgan R. Gostel   +6 more
wiley   +1 more source

A Scalable Large Language Model‐Aided Approach for Mining Plant‐Compound Pairs From Scientific Literature

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding plant chemicals is vital for medicine and agriculture, but global data remain fragmented and biased. We developed an AI‐powered tool to automatically extract plant‐compound information from scientific literature at scale and low cost. Our analysis revealed significant knowledge gaps, particularly in the Southern Hemisphere. By efficiently
Adam Richard‐Bollans, Francesco Civita
wiley   +1 more source

When alien plants become health hazards: An applied study on toxic and allergenic risks in Italy

PLANTS, PEOPLE, PLANET, EarlyView.
Alien plants are often studied for their ecological harm, but their risks to human and animal health remain poorly documented. This study provides the first comprehensive catalogue of poisonous and allergenic alien plants in Italy, identifying which species are dangerous, where they grow and who is most at risk—from children in city parks to pets and ...
Giulio Barone, Gianniantonio Domina, Giuseppe Venturella, Emilio Di Gristina   +3 more
wiley   +1 more source