Results 61 to 70 of about 144,211 (333)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Diet selection and performance of horses grazing on different heathland types

Animal, 2017
The number of horses in northern Spanish mountains has increased in recent decades, but little is known about their grazing behaviour, performance and potential for foal meat production.
C. López López, L.M.M. Ferreira, U. García, J. Moreno-Gonzalo, M.A.M. Rodrigues, K. Osoro, I. Ferre, R. Celaya   +7 more
doaj   +1 more source

Identification of long-chain alkane-degrading (LadA) monooxygenases in Aspergillus flavus via in silico analysis

Frontiers in Microbiology, 2022
Efficient degradation of alkanes in crude oil by the isolated Aspergillus flavus MM1 alluded to the presence of highly active alkane-degrading enzymes in this fungus. A long-chain alkane-degrading, LadA-like enzyme family in A. flavus was identified, and
Madushika Perera, Sulochana Wijesundera, C. Dilrukshi Wijayarathna, Gamini Seneviratne, Sharmila Jayasena   +4 more
doaj   +1 more source

Room Temperature Acceptorless Alkane Dehydrogenation from Molecular σ-Alkane Complexes [PDF]

Journal of the American Chemical Society, 2019
The non-oxidative catalytic dehydrogenation of light alkanes via C-H activation is a highly endothermic process that generally requires high temperatures and/or a sacrificial hydrogen acceptor to overcome unfavorable thermodynamics. This is complicated by alkanes being such poor ligands, meaning that binding at metal centers prior to C-H activation is ...
Alasdair I. McKay, Alexander J. Bukvic, Bengt E. Tegner, Arron L. Burnage, Antonio J. Martı́nez-Martı́nez, Nicholas H. Rees, Stuart A. Macgregor, Andrew S. Weller   +7 more
openaire   +6 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Comparative Genomic Analysis and Functional Identification of CER1 and CER3 Homologs in Rice Wax Synthesis

Biology
Alkane is a predominant wax component, whose production requires the aids of CER1 and CER3. In rice, OsCER1 and OsCER3 are present in multiple copies. Until now, the roles of these genes have been studied individually; however, a systematic comparison of
Nesma E. E. Youssif, Bowen Yang, Haodong Huang, Mohamed Hamdy Amar, Mohamed Ezzat, Mohammad Belal, Sanaa A. M. Zaghlool, Huayan Zhao, Dong Fu, Shiyou Lü   +9 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Bioremediation of Oil-Contaminated Soil of the Republic of Kazakhstan Using a New Biopreparation

Microorganisms, 2023
A new biopreparation is developed to clean soils from oil pollution in the arid climate of the Republic of Kazakhstan. The biopreparation includes bacterial strains R. qingshengii F2-1, R. qingshengii F2-2, and P. alloputida BS3701.
Tatiana Vyacheslavovna Funtikova, Lenar Imametdinovich Akhmetov, Irina Filippovna Puntus, Pavel Alexeevich Mikhailov, Nurbol Orynbasaruly Appazov, Roza Abdibekovna Narmanova, Andrey Evgenievich Filonov, Inna Petrovna Solyanikova   +7 more
doaj   +1 more source

n-Alkanes and n-Alkenes in Virgin Olive Oil from Calabria (South Italy): The Effects of Cultivar and Harvest Date [PDF]

, 2021
Angelo Maria Giuffrè
openalex   +1 more source

Roman diet and trade: evidence from organic residues on pottery sherds recovered at the Roman town of Calleva Atrebatum (Silchester Hants.) [PDF]

, 2008
The analysis of organic residues from pottery sherds using Gas-Chromatography with mass-spectroscopy (GC-MS) has revealed information about the variety of foods eaten and domestic routine at Silchester between the second and fourth–sixth centuries A.D ...
Copley, Evershed, Fulford, Heron, Holbrook, Ingrem, L.-J. Marshall, M.G. Fulford, M.J. Almond, Mills, Orton, Pollard, Robinson, S.R. Cook, Serpico, Timby, Tyers   +16 more
core   +1 more source