Results 121 to 130 of about 80,529 (226)

In Situ Evaluation of the GSH Depletion Ability of Various Alkylating Agents and the Protective Effect of Several Active Thiol Compounds Based on High-Content Cell Analysis. [PDF]

Toxics
Guo J, Li Z, Wang J, Ma B, Zhang L, Wang H, Wu J, Xie J.   +7 more
europepmc   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Chemotherapy with Alkylating Agents and Dental Anomalies in Children: A Systematic Review. [PDF]

J Clin Med
Gallenzi P, Malatesta A, Staderini E, Guglielmi F.   +3 more
europepmc   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents. [PDF]

Neoplasia
Caggiano R, Prokhorova E, Duma L, Schützenhofer K, Lauro R, Catara G, Melillo RM, Celetti A, Smith R, Weroha SJ, Kaufmann SH, Ahel I, Palazzo L.   +12 more
europepmc   +1 more source

Assessing the Health Impacts of Contaminants on Green Turtles (Chelonia mydas) Along the Southern Coast of Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Chemical pollutants pose a significant threat to marine ecosystems. Among these contaminants are trace elements and polycyclic aromatic hydrocarbons (PAH). Green turtles can be employed to evaluate the oceans' health due to their coastal habitats and exposure to multiple threats.
Camila Roberta da Silva Ribeiro, Andressa Maria Rorato Nascimento de Matos, Eloiza Teles Caldart, Liana Rosa, Camila Domit, Guilherme dos Santos Lima, Ana Paula Frederico Rodrigues Loureiro Bracarense   +6 more
wiley   +1 more source

Alkylating agents-induced gonadotoxicity in prepubertal males: Insights on the clinical and preclinical front. [PDF]

Clin Transl Sci
Sriram S, Macedo T, Mavinkurve-Groothuis A, van de Wetering M, Looijenga LHJ.   +4 more
europepmc   +1 more source

Mutation signatures specific to DNA alkylating agents in yeast and cancers. [PDF]

Nucleic Acids Res, 2020
Saini N, Sterling JF, Sakofsky CJ, Giacobone CK, Klimczak LJ, Burkholder AB, Malc EP, Mieczkowski PA, Gordenin DA.   +8 more
europepmc   +1 more source

The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents. [PDF]

Acta Neuropathol Commun, 2021
Siller S, Lauseker M, Karschnia P, Niyazi M, Eigenbrod S, Giese A, Tonn JC.   +6 more
europepmc   +1 more source

Oxidative Stress Biomarkers in the Shrimp Macrobrachium amazonicum (Heller, 1862): Assessment in an Environmental Preservation Area in the Brazilian Amazon

Environmental Toxicology, EarlyView.
ABSTRACT Anthropogenic activities generate a significant amount of pollutants that are released into the environment, causing physiological and ecological disturbances. Among the xenobiotics present in aquatic ecosystems, numerous chemical and organic compounds have oxidative potential or are metabolized through oxidative processes, which may amplify ...
Natália Eduarda da Silva, Arllon José dos Santos Dias, Layane Vitoria dos Santos e Santos, Natalie de Matos Araujo, Darlan Coutinho dos Santos, Jefferson Romáryo Duarte da Luz, Gabriel Araujo‐Silva   +6 more
wiley   +1 more source