Results 151 to 160 of about 3,196,403 (286)
Induction of specific Escherichia coli genes by sublethal treatments with alkylating agents. [PDF]
, 1984 Michael R. Volkert, Dinh C. Nguyen
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Clickable Pyclen‐Based Luminescent Lanthanide Complexes: Application to Two‐Photon Microscopy
Chemistry – A European Journal, EarlyView.This work presents two pyclen‐based lanthanide complexes (Eu3+ and Sm3+) bearing an alkynyl‐linker dedicated to bioconjugation. Featuring strong luminescence and two‐photon (2P) absorption, they were conjugated to a cell‐penetrating peptide thanks to copper‐catalyzed azide‐alkyne cycloaddition. The resulting luminescent conjugates reach efficiently the
Baptiste Chartier +13 more
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ChemMedChem, EarlyView.BP(1‐6) compounds designed from Benzoxazole and Thiazolyl‐Pyrazole scaffolds exhibited potent antitubulin and caspase‐3 activity in MDA‐MB‐231 cells. BP‐6 notably triggered apoptosis and disrupted cell proliferation. Docking studies validated strong binding affinities of BP‐2 and BP‐6 toward β‐tubulin and caspase‐3, suggesting promising therapeutic ...
Burak Kuzu +3 more
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Chemistry–Methods, EarlyView.Heterohelicenes with multiple chiral axes have the potential to drive next‐generation technologies due to their unique structural and optoelectronic features. This review highlights innovative short‐step synthetic strategies for double and triple heterohelicenes, emphasizing their ease of preparation and valuable (chir)optical features, along with high
Mohamed S. H. Salem, Shinobu Takizawa
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Chemistry–Methods, EarlyView.Etched silicon powder‐supported Pd is developed as a durable and efficient catalyst for continuous flow hydrogenation and reductive alkylation. This study develops a novel heterogeneous palladium catalyst immobilized on etched silicon powder, demonstrating high efficiency and long‐term stability under continuous flow conditions.
Zhenzhong Zhang +4 more
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The Alkylating Agent, Dimethyl Sulphate, Stimulates ADP‐Ribosylation of Histone H1 and Other Proteins in Permeabilised Mouse Lymphoma (L1210) Cells [PDF]
, 1982 Nguyen thi Mân, Sydney Shall
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Clinical Pharmacology &Therapeutics, EarlyView.Busulfan is administered intravenously in conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT), with model‐informed precision dosing (MIPD) targeting a 4‐day cumulative AUC of 80–100 mg*hour/L. Three pharmacokinetic (PK) models—Bognar, Langenhorst, and McCune—were evaluated using data with a minimum of 1 and a median
Rashudy F. Mahomedradja +13 more
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