Results 181 to 190 of about 86,457 (338)
Environmental and Molecular Mutagenesis, EarlyView.Abstract As a part of the International Workshop on Genotoxicity Testing (IWGT) in 2022, a workgroup was formed to evaluate the level of validation and regulatory acceptance of transcriptomic biomarkers that identify genotoxic substances. Several such biomarkers have been developed using various molecular techniques and computational approaches. Within
Matthew J. Meier +7 more
wiley +1 more source
Food Safety and Health, EarlyView.Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie +3 more
wiley +1 more source
Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation. [PDF]
Int J Mol Sci, 2021 Ullmann R +11 more
europepmc +1 more source
Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis
Journal of Periodontology, EarlyView.Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos +8 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching +2 more
wiley +1 more source
The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model. [PDF]
Hum Reprod, 2021 Del Castillo LM +10 more
europepmc +1 more source
Poly(sarcosine) Lipid Synthesis From CO2‐Based Sarcosine‐N‐Carboxyanhydride
Macromolecular Rapid Communications, EarlyView.In this work, we optimize and scale‐up a CO2‐based synthesis of sarcosine‐N‐carboxyanhydride (Sar‐NCA) to the gram scale. The low toxicity and simplicity of the approach make it an attractive alternative to current toxic phosgene‐based approaches. The CO2‐based Sar‐NCA has sufficient purity for controlled polymerization.
Florian T. Kaps +7 more
wiley +1 more source