Results 51 to 60 of about 3,238,601 (165)
Theoretical kinetic study of thermal unimolecular decomposition of cyclic alkyl radicals [PDF]
J. Phys. Chem. A 112, 46 (2008) 11598-11610, 2009 While many studies have been reported on the reactions of aliphatic hydrocarbons, the chemistry of cyclic hydrocarbons has not been explored extensively. In the present work, a theoretical study of the gas-phase unimolecular decomposition of cyclic alkyl radicals was performed by means of quantum chemical calculations at the CBS-QB3 level of theory ...
arxiv
Alkylating agents in membranous nephropathy: efficacy proven beyond doubt.
Nephrology, Dialysis and Transplantation, 2010 Idiopathic membranous nephropathy (iMN) is one of the most common causes of the nephrotic syndrome in adults. The clinical course of patients with iMN is quite variable.
J. Hofstra, J. Wetzels
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Clinical Cancer Research, 2008 Purpose: Bendamustine has shown clinical activity in patients with disease refractory to conventional alkylator chemotherapy. The purpose of this study was to characterize the mechanisms of action of bendamustine and to compare it with structurally ...
L. Leoni +7 more
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Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma
Clinical Cancer Research, 2008 Intrinsic or acquired chemoresistance to alkylating agents is a major cause of treatment failure in patients with malignant brain tumors. Alkylating agents, the mainstay of treatment for brain tumors, damage the DNA and induce apoptosis, but the ...
J. Sarkaria +6 more
semanticscholar +1 more source
Surface Structure of Organoclays [PDF]
arXiv, 2003 The properties of organically modified clay minerals determine essentially the quality of polymer-clay nanocomposites. We investigate alkylammonium-micas with different alkyl chain length by molecular dynamics simulation as homogeneous mixtures and separated island structures on the mica surface (80 percent alkali exchange, 20 percent of the alkali ...
arxiv
The Physics of Antimicrobial Activity of Ionic Liquids [PDF]
arXivThe bactericidal potency of ionic liquids (ILs) is well-established, yet their precise mechanism of action remains elusive. Here, we show evidence that the bactericidal action of ILs primarily involves permeabilizing the bacterial cell membrane.
arxiv
NAD+ Acts as a Protective Factor in Cellular Stress Response to DNA Alkylating Agents. [PDF]
Cells, 2023 Ruszkiewicz J +10 more
europepmc +1 more source
Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans. [PDF]
Cells, 2023 Ruszkiewicz J +4 more
europepmc +1 more source
Structure and Phase Transitions of Alkyl Chains on Mica [PDF]
J. Am. Chem. Soc. 2003, 125, 9500-9510, 2003 We use molecular dynamics as a tool to understand the structure and phase transitions [Osman et. al. J. Phys. Chem. B 2000, 104, 4433; 2002, 106, 653] in alkylammonium micas. The consistent force field 91 is extended for accurate simulation of mica and related minerals.
arxiv
A Comparison of Several Modern Alkylating Agents
, 2009 This review covers the application, mechanisms and limitations of simple alkylating agents that can be used for the conversion of carboxylic acids to esters, phenols to aryl ethers, enols to enol ethers and thiols to thioethers.
Guy Lamoureux, C. Agüero
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