Results 91 to 100 of about 89,156 (285)

Mixed‐Metal Ce‐Zr‐Mn Clusters as Photo‐Catalysts for Decarboxylative Functionalization of Carboxylic Acids

Angewandte Chemie, EarlyView.
Decarboxylative hydrazination of carboxylic acids is achieved using a 1:5:2 ratio of three metal salts, Ce(OtBu)4, Zr(OtBu)4, and Mn(OAc)3, as a catalyst under visible light irradiation, in which single cerium‐incorporated hexanuclear mixed‐metal clusters containing a [CeZr5O4(OH)4]12+ core are formed with association of manganese(II) species.
Sota Tamaki, Riina Kuwata, Shuto Wakita, Yasuko Osakada, Mamoru Fujitsuka, Tetsuro Kusamoto, Kazushi Mashima, Hayato Tsurugi   +7 more
wiley   +2 more sources

Interrupted Barton–Zard Reaction/Friedel–Crafts Alkylation Telescoped Reaction for the Synthesis of Pyrrolo[3,4‐b]indole Cores

Asian Journal of Organic Chemistry, EarlyView.
An interrupted Barton–Zard reaction/Friedel–Crafts alkylation telescoped reaction provides aryl‐substituted pyrrolo[3,4‐b] cores in moderate‐to‐good yields as mostly single diastereomers. The reaction is tolerant of a wide range of electron‐deficient indoles and (hetero)aromatic nucleophiles, offering a modular approach for the synthesis of multi ...
Josip Rešetar, Karla Remar, Ana Mikleušević, Josipa Suć Sajko, Ines Bašić, Matija Gredičak   +5 more
wiley   +1 more source

Lewis Acidity of the SbCl3/o‐chloranil System

Angewandte Chemie, EarlyView.
An SbCl5 surrogate from easy‐to‐handle reagents! The putative SbCl3(o‐C6O2Cl4) synthon is calculated to be more Lewis acidic than SbCl5. Even if endergonic, its formation from SbCl3 and o‐chloranil can be driven by Lewis base coordination, leading to the corresponding adducts.
Ferit Şit, Nathanael H. Hunter, Logan T. Maltz, François P. Gabbaï   +3 more
wiley   +2 more sources

Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis

Asian Journal of Organic Chemistry, EarlyView.
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley   +1 more source

Engineered C–N Lyases for Stereoselective Synthesis of Tertiary Amines

Angewandte Chemie, EarlyView.
EDDS lyase was subjected to iterative cycles of site‐saturation mutagenesis and screened for increased activity for the addition of 2‐((methylamino)methyl)aniline to fumarate. The final mutant, EDDS lyase CEA, accepts various N‐methyl‐1‐phenylmethanamines derivatives, yielding N,N‐disubstituted L‐aspartic acids, as well as several ortho‐substituted ...
Laura Bothof, Xiaofang Gong, Marrit E. Onclin, Peter Fodran, Gerrit J. Poelarends   +4 more
wiley   +2 more sources

Sodium Hydroxide in Alcohol as a Base for the Alkylation of Ethyl Acetoacetate. [PDF]

, 1959
Arne Brändström, E. J. Matikkala, Svend E. Hansen, R. Sömme, Einar Stenhagen, H. Palmstierna   +5 more
openalex   +1 more source

Exploiting 3‐Methyleneisoindolinones as In Situ Generated Reactive Intermediates in the Synthesis of Tetrasubstituted Carbon Center

Asian Journal of Organic Chemistry, EarlyView.
A straightforward method for constructing a tetrasubstituted carbon center through the in situ formation of 3‐methyleneisoindolinones as reactive intermediates has been developed. This process involves an acid‐catalyzed Meyer‐Schuster rearrangement of isoindolinone‐based propargylic alcohols, followed by an intermolecular Friedel‐Crafts alkylation ...
Arben Beriša, Filip Duplić, Marko Purić, Matija Gredičak, Nikola Topolovčan   +4 more
wiley   +1 more source

Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates

Angewandte Chemie, EarlyView.
Aziridination of alkenes is an important route to chiral nitrogen‐containing building blocks. We report that carbamate‐functionalized allylic alcohols undergo highly enantioselective aziridination using achiral dimeric Rh complexes ion‐paired with cinchona alkaloid‐derived chiral cations.
Arthur R. Lit, Shotaro Takano, Christian Zachau, Ioana Băltărețu, Robert J. Phipps   +4 more
wiley   +2 more sources

The Synthesis of Cyclopropyl‐Fused Tetrahydrofurans from Vinylcyclopropanes

Asian Journal of Organic Chemistry, EarlyView.
Vinylcyclopropanes undergo iodocyclization to afford a series of oxabicyclo[3.1.0]hexanols. These substrates were shown to be useful intermediates for the construction of various cyclopropyl‐fused polycycles. Abstract The rapid synthesis of oxabicyclo[3.1.0]hexanols from various vinylcyclopropanes is described.
Alexander J. Craig, Andrew P. Cording, Selena C. L. Gilmer, Jackson S. Henneveld, Sinan Gai, Owain H. Harker, Nigel T. Lucas, Bill C. Hawkins   +7 more
wiley   +1 more source

Asymmetric Intramolecular α‐Arylation of Polar Amino Acids Bearing β‐Leaving Groups

Angewandte Chemie, EarlyView.
Use of enolate chemistry to functionalise amino acids with β‐heteroatom side‐chains (serine, cysteine, threonine, etc.) is hampered by β‐elimination. We show that α‐arylation can be achieved by incorporating the side chain into a saturated heterocycle, making the unwanted elimination a disfavoured 5‐endo‐trig reaction.
Ömer Taspinar, Daniel J. Leonard, Nathan Picois, Cornelia Göcke, Matej Žabka, Hazel A. Sparkes, Jonathan Clayden   +6 more
wiley   +2 more sources