Results 271 to 280 of about 166,984 (347)

Catalytic Enantioselective Alkylation of Prochiral Enolates.

Chemical Reviews, 2021
The asymmetric alkylation of enolates is a particularly versatile method for the construction of α-stereogenic carbonyl motifs, which are ubiquitous in synthetic chemistry.
Timothy B. Wright, P. Evans
semanticscholar   +1 more source

Beyond Friedel and Crafts: Directed Alkylation of C−H Bonds in Arenes

Angewandte Chemie - International Edition, 2019
Alkylation of arenes is one of the most fundamental transformations in chemical synthesis and leads to privileged scaffolds in many areas of science. Classical methods for the introduction of alkyl groups to arenes are mostly based on the Friedel-Crafts ...
Gwilherm Evano, Cedric Theunissen
exaly   +2 more sources

B(C6F5)3-Catalyzed Direct C3 Alkylation of Indoles and Oxindoles

ACS Catalysis, 2020
The direct C3 alkylation of indoles and oxindoles is a challenging transformation, and only a few direct methods exist. Utilizing the underexplored ability of triaryl boranes to mediate the heterolytic cleavage of α-nitrogen C–H bonds in amines, we have ...
Shyam Basak, Rebecca L Melen, Louis C Morrill   +2 more
exaly   +2 more sources

Visible-Light-Promoted C(sp3)-H Alkylation by Intermolecular Charge Transfer: Preparation of Unnatural α-Amino Acids and Late-stage Modification of Peptides.

Angewandte Chemie, 2020
Disclosed herein is the visible-light promoted deaminative C(sp3)-H alkylation of glycine and peptides using Katritzky salts as electrophiles. Simple reaction conditions and excellent functional-group tolerance provided a general strategy for the ...
Chao Wang, Rupeng Qi, H. Xue, Yuxuan Shen, M. Chang, Yaqiong Chen, Rui Wang, Zhao-Qin Xu   +7 more
semanticscholar   +1 more source

Polarity Umpolung Strategy for the Radical Alkylation of Alkenes.

Angewandte Chemie, 2020
Free radical-mediated alkylation of general alkenes is a challenging and largely unmet goal. Herein, we disclose a conceptually novel "polarity umpolung" strategy for radical alkylation of alkenes using a portfolio of easily-accessed, dual-function ...
Jige Liu, Shuo Wu, Jiajia Yu, Chenxi Lu, Zhen Wu, Xinxin Wu, Xiao-song Xue, Chen Zhu   +7 more
semanticscholar   +1 more source

Manganese-Catalyzed α-Alkylation of Ketones, Esters, and Amides Using Alcohols

ACS Catalysis, 2018
Herein we report the manganese-catalyzed C–C bond-forming reactions via α-alkylation of ketones, amides, and esters, using primary alcohols. β-Alkylation of secondary alcohols by primary alcohols to obtain α-alkylated ketones is also reported.
Subrata Chakraborty, Prosenjit Daw, David Milstein   +2 more
exaly   +2 more sources

Analysis of alkyl phosphates by extractive alkylation

Bulletin of Environmental Contamination and Toxicology, 1981
The development of suitable methods for analysis of the alkyl phosphate metabolites of organophosphorus pesticides in urine has been a rather d i f f i cu l t and persistent problem. Currently available methodology (BRADWAY et al. 1977; LORES & BRADWAY 1977; SHAFIK et al. 1973) suffers from several shortcomings.
D E, Bradway, R, Moseman, R, May
openaire   +2 more sources

Beyond Friedel and Crafts: Innate Alkylation of C−H Bonds in Arenes

Angewandte Chemie - International Edition, 2019
Alkylated arenes are ubiquitous molecules and building blocks commonly utilized in most areas of science. Despite its apparent simplicity, the regioselective alkylation of arenes is still a challenging transformation in a lot of cases.
Gwilherm Evano, Cedric Theunissen
exaly   +2 more sources

Guanidine Alkylation

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
I. A. Larionova, A. V. Golounin, V. A. Sokolenko   +2 more
openaire   +1 more source

Visible-Light-Driven N-Heterocyclic Carbene-catalyzed γ- and ε-Alkylation with Alkyl Radicals.

Angewandte Chemie, 2019
The merging of photoredox catalysis and N-heterocyclic carbene (NHC) catalysis for γ- and ε-alkylation of enals with alkyl radicals was developed.
L. Dai, Zi-Hao Xia, Yuan-Yuan Gao, Zhong-Hua Gao, Song Ye   +4 more
semanticscholar   +1 more source