Results 271 to 280 of about 196,557 (349)

Development of a Sustainable Technology Platform for the Homogeneous Friedel-Crafts Alkylation using Acidic Ionic Liquid Catalyst

, 2009
Joni Joni
openalex   +1 more source

Remarkable Formation of Indene Derivatives Upon Friedel–Crafts Acylation Reactions

European Journal of Organic Chemistry, EarlyView.
This shows indene derivatives. Under the reaction conditions of a Friedel–Crafts acylation, alkyl benzenes underwent an unprecedented cyclopentannulation furnishing indene derivatives. Alkylbenzene derivatives react with two equivalents of pivaloyl chloride (PivCl) in the presence of aluminum trichloride under formation of indene derivatives with up to
Leah Bantel, Neels Kruse, Marc Schmidtmann, Jens Christoffers   +3 more
wiley   +1 more source

Photoredox/Nickel Dual-Catalyzed Asymmetric C-Alkylation of Nitroalkanes with α-Bromoketones. [PDF]

Org Lett
Rezazadeh S, Kim RS, Watson DA.
europepmc   +1 more source

Memory of Chirality in Radical Addition–Translocation–Cyclization Cascades

Helvetica Chimica Acta, EarlyView.
Radical addition–translocation–cyclization cascades of chiral alkynes show striking memory of chirality (MoC), with strong retention of configuration when fast, polarity favored cyclization are involved. The most effective system employs a highly electron‐poor pentafluorobenzenesulfonyl group.
Christian Simon Gloor, Fabrice Dénès, Valentin Soulard, Philippe Renaud   +3 more
wiley   +1 more source

Iridium-Catalyzed Stereoselective α-Alkylation of α-Hydroxy Ketones with Minimally Polarized Alkenes. [PDF]

J Am Chem Soc
Wang Y, Hong F, Robertson CM, Mudd RJ, Bower JF.   +4 more
europepmc   +1 more source

Photoresponsive Metallo‐Supramolecular Systems Constructed From a Bidentate Ligand

Macromolecular Rapid Communications, EarlyView.
Metallosupramolecular polymer organogels based on dynamic metal–ligand (ML) cross‐links are rendered optically responsive by incorporating a photoacid generator. Exposing these systems to UV light releases an acid that protonates the ligands, causing network disassembly and thereby softening.
Luca Bertossi, Carina Lin, Davide M. De Luca, Marta Oggioni, Georges J. M. Formon, Christoph Weder   +5 more
wiley   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

PROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong, Yuming Shi, Aleksandra Kozlova, Renata Moravcova, Jason C. Rogalski, Aidan Jamieson, Lance Lansing, Kyung‐Mee Moon, Xiaojing Yuan, Amanda S. Gregoris, Heather Higo, Julia Common, Ida M. Conflitti, Mateus Pepinelli, Lan Tran, Morgan Cunningham, Hosna Jabbari, Syed Abbas Bukhari, Sarah K. French, Rodrigo Ortega Polo, Shelley E. Hoover, Stephen F. Pernal, Pierre Giovenazzo, M. Marta Guarna, Amro Zayed, Leonard J. Foster   +25 more
wiley   +1 more source