Results 281 to 290 of about 166,984 (347)

Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation.

Journal of the American Chemical Society, 2019
Histidine (His) carries a unique heteroaromatic imidazole side chain and plays irreplaceable functional roles in peptides and proteins. Existing strategies for site-selective histidine modification predominantly rely on the N-substitution reactions of ...
Xiaoping Chen, Farong Ye, Xiaosheng Luo, Xueyi Liu, Jie Zhao, Siyao Wang, Qingqing Zhou, Gong Chen, Ping Wang   +8 more
semanticscholar   +1 more source

Alkylating enzymes

Current Opinion in Chemical Biology, 2013
Chemospecific and regiospecific modifications of natural products by methyl, prenyl, or C-glycosyl moieties are a challenging and cumbersome task in organic synthesis. Because of the availability of an increasing number of stable and selective transferases and cofactor regeneration processes, enzyme-assisted strategies turn out to be promising ...
Ludger A Wessjohann, Jeanette Keim, Benjamin Weigel, Martin Dippe   +3 more
openaire   +2 more sources

Visible-Light-Initiated Decarboxylative Alkylation of Quinoxalin-2(1H)-ones with Phenyliodine(III) Dicarboxylates in Recyclable Ruthenium(II) Catalytic System

ACS Sustainable Chemistry and Engineering, 2019
A efficient and sustainable approach for the synthesis of 3-alkylquinoxalin-2(1H)-ones has been developed through visible-light-mediated decarboxylative alkylation of quinoxalin-2(1H)-ones with phenyliodine(III) dicarboxylates.
Long‐Yong Xie, Li-Lin Jiang, Jia-Xi Tan, Yi Wang, Xiang-Qin Xu, Bo Zhang, Zhong Cao, Weimin He   +7 more
semanticscholar   +1 more source

The Alkylating Properties of Alkyl Thiophosphates

Angewandte Chemie International Edition in English, 1965
AbstractThiophosphate and phosphate esters have been synthesized in great variety since about 1945, and are being produced in increasing quantities, mainly for plant protection. An important property of alkyl phosphates and thiophosphates is their alkylating power, which is comparable with that of dialkyl sulfates and alkyl p‐toluenesulfonates.
G. Hilgetag, H. Teichmann
openaire   +1 more source

Enantioselective Allylic Alkylation with 4-Alkyl-1,4-dihydro-pyridines Enabled by Photoredox/Palladium Cocatalysis.

Journal of the American Chemical Society, 2018
Highly regio- and enantioselective allylic alkylation has been achieved enabled by the merger of photoredox and palladium catalysis. In this dual catalytic process, alkyl radicals generated from 4-alkyl-1,4-dihydropyridines act as the coupling partners ...
Honghao Zhang, Jia-Jia Zhao, Shouyun Yu
semanticscholar   +1 more source

Alkyl Glucosides

Dermatitis®, 2017
Alkyl glucosides are surfactants synthesized through the condensation of long-chain fatty alcohols and glucose, extracted from vegetal, renewable sources. Although available for more than 4 decades, they have been rediscovered in recent years because of their eco-friendly character.
Maisa, Alfalah, Camille, Loranger, Denis, Sasseville   +2 more
openaire   +2 more sources

Reductive alkyl–alkyl coupling from isolable nickel–alkyl complexes

Nature
The selective cross-coupling of two alkyl electrophiles to construct complex molecules remains a challenge in organic synthesis1,2. Known reactions are optimized for specific electrophiles and are not amenable to interchangeably varying electrophilic substrates that are sourced from common alkyl building blocks, such as amines, carboxylic acids and ...
Samir Al Zubaydi, Shivam Waske, Volkan Akyildiz, Hunter F. Starbuck, Mayukh Majumder, Curtis E. Moore, Dipannita Kalyani, Christo S. Sevov   +7 more
openaire   +3 more sources

The Combination of Benzaldehyde and Nickel-Catalyzed Photoredox C(sp3 )-H Alkylation/Arylation.

Angewandte Chemie, 2019
Herein we report a highly selective photoredox C(sp3 )-H alkylation/arylation of ethers through the combination of a photo-organocatalyst (benzaldehyde) and a transition-metal catalyst (nickel).
Lumin Zhang, Xiaojia Si, Yangyang Yang, M. Zimmer, Sina Witzel, K. Sekine, M. Rudolph, A. Hashmi   +7 more
semanticscholar   +1 more source

Catalytic alkylation of unactivated C(sp3)-H bonds for C(sp3)-C(sp3) bond formation.

Chemical Society Reviews, 2019
The construction of carbon-carbon bonds is a central tenet of modern synthetic chemistry. Metal-catalyzed C-H functionalization can serve as a particularly powerful tool for achieving carbon-carbon bond formation.
Zhen Chen, Meng Rong, J. Nie, Xue-Feng Zhu, Bingfeng Shi, Jun‐An Ma   +5 more
semanticscholar   +1 more source

C‐Alkylation of Ketones and Related Compounds by Alcohols: Transition‐Metal‐Catalyzed Dehydrogenation

Angewandte Chemie - International Edition, 2016
Fei Huang, Zhuqing Liu, Zhengkun Yu
exaly   +2 more sources