Results 81 to 90 of about 89,156 (285)
Aggregate, EarlyView.A domino reaction leading to the novel heterocyclic aggregate 2,9‐dihydrobenzo[b]cyclopenta[e][1,4]thiazine has been developed, with its mechanism elucidated by crystallography and ESI‐MS to reveal a 15‐step reaction sequence (the longest reported to date) involving intermolecular C‐C coupling and intramolecular expansion.
Kai‐Bin Chen +9 more
wiley +1 more source
AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing
Advanced Intelligent Discovery, EarlyView.AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley +1 more source
Amide Chemistry Enables Redox Locking of Cyclic Disulfides for Polypeptide Assembly
Angewandte Chemie, EarlyView.The stability of a family of cyclic dichalcogenides derived from cysteine is significantly enhanced against reductants upon acylation of the alpha‐amino group. Amide formation serves as a redox lock, offering a mechanism to achieve selectivity in the assembly of large cyclic polypeptides on a water‐compatible solid support.
Vincent Diemer +4 more
wiley +2 more sources
Advanced Intelligent Systems, EarlyView.A novel approach integrates gas chromatography‐mass spectrometry with infrared, Raman, and nuclear magnetic resonance spectroscopy plus density functional theory to detect synthetic drugs. Quantum hyperpolarization further boosts NMR sensitivity for low‐concentration samples, improving detection accuracy in complex mixtures and offering promising ...
Keunhong Jeong +8 more
wiley +1 more source
Alkylation of Carbohydrates with Alkyl Trifluoromethanesulfonates. [PDF]
Acta Chemica Scandinavica, 1978 Jan Arnarp +5 more
openaire +2 more sources
Asian Journal of Organic Chemistry, EarlyView.A facile synthetic route to (−)‐8a‐epi‐lentiginosine from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji–Trost reaction of non−derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring is reported. The crystal structure of (−)‐8a‐epi‐lentiginosne showed the envelope conformation of the five‐membered ring ...
Sunisa Akkarasamiyo +3 more
wiley +1 more source
N‐Insertion of Diazonium Salts Into Ketone Derivatives
Angewandte Chemie, EarlyView.Diazonium salts insert into ketones and their silyl enol ethers through a sequence of α‐azenylation and ring expansion via an N‐iminoaziridinium species. Coupled with an efficient N‐N bond cleavage, this protocol offers a mild alternative to Beckmann rearrangements and a powerful tool for skeletal editing of ketones.
Mohammed Anif Pasha +3 more
wiley +2 more sources
Asian Journal of Organic Chemistry, EarlyView.Ir‐catalyzed sulfur‐directed C─H alkenylation of alkynoates proceeded by using aryl methallyl sulfides. When DMAD was employed, 1,3‐dienes were initially formed and subsequently underwent thermal 1,5‐sigmatropic rearrangement to yield secondary products with high stereoselectivitiy.
Takanori Shibata, Haru Marumo
wiley +1 more source