Whole cell studies of substrate and inhibitor specificity of isoprene monooxygenase and related enzymes [PDF]
Co-oxidation of a range of alkenes, dienes, and aromatic compounds by whole cells of the isoprene-degrading bacterium Rhodococcus sp. AD45 expressing isoprene monooxygenase was investigated, revealing a relatively broad substrate specificity for this ...
Crombie, Andrew +7 more
core +1 more source
Endogenous Alkylglycerol Functions As a Mediator of Protein Kinase C Activity and Cell Proliferation [PDF]
To explore the possibility that 1-O-alkyl-sn-glycerol (alkylglycerol) may serve a regulatory role in the control of cell proliferation or PKC activity, we examined the ability of alkylglycerol to influence PKC activity and subcellular distribution as ...
Buchanan, Fritz G.
core +1 more source
Converting Phenylacetone Monooxygenase into Phenylcyclohexanone Monooxygenase by Rational Design:Towards Practical Baeyer-Villiger Monooxygenases [PDF]
A homology model of the most frequently used, but thermally somewhat labile, Baeyer–Villiger monooxygenase, cyclohexanone monooxygenase (CHMO) has been derived on the basis of the recently published crystal structure of the thermally stable phenylacetone
Schulz, Frank +11 more
core +1 more source
Genetic variation in the FMO2 gene: evolution & functional consequences [PDF]
PhDFlavin-containing monooxygenase 2 (FMO2) is involved in the metabolism of xenobiotics, including therapeutic drugs. FMO2 exists in two forms: a functional and a non-functional form.
Al-Sulaimani, Maha Saleh
core +2 more sources
Challenging mechanistic paradigms in copper monooxygenase [PDF]
This work explores the structure and function of an important copper monooxygenase: peptidylglycine alpha-amidating monooxygenase. The canonical reaction mechanism of this enzyme is discussed, including its strengths and weaknesses.
Welch, Evan
core +1 more source
Estimated levels of cytochrome P450s (representing monooxygenase activity) in the An. funestus population of Tihuquine compared with An. gambiae Kisumu reference strain.
Nelson Cuamba (364349) +4 more
core +1 more source
Editorial: Insights in experimental pharmacology and drug discovery: 2022. [PDF]
Latini A, Uroz CP, Trostchansky A.
europepmc +1 more source
Diversity, mutagenesis and recombinant expression of the soluble methane monooxygenase [PDF]
Methanotrophic bacteria convert methane to methanol using a methane monooxygenase enzyme (MMO). Two types of MMO exist: a membrane bound enzyme (PMMO) and a cytoplasmic enzyme (sMMO).
Dumont, Marc G.
core
The purification of ammonia monooxygenase fromParacoccus denitrficans
The heterotrophic nitrifier Paracoccus denitrificans expresses a membrane-associated ammonia monooxygenase. The active enzyme has been solubilized in the detergent dodecyl-β-d-maltoside and purified by standard chromatographic techniques.
David J. Richardson +7 more
core +1 more source

