Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]
, 2015 The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy +3 more
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N-(2-Phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl)methane Sulfonamide
Molbank, 2012 The title compound, N-(2-phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl) methanesulfonamide was synthesized in high yield by Sonogashira cross coupling of N-(4-iodo-2-phenoxyphenyl)methanesulfonamide with 3-phenoxyprop-1-yne.
Shylaprasad Durgadas +2 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title molecule, C20H15NO3, adopts a Z-shaped conformation with the carboxyl group nearly coplanar with the dihydroquinoline unit. In the crystal, corrugated layers are formed by C—H...O hydrogen bonds and are stacked by C—H...π(ring) interactions ...
Younos Bouzian +5 more
doaj +1 more source
Mechanism, reactivity, and selectivity of nickel-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes. [PDF]
, 2014 Density functional theory (DFT) calculations with B3LYP and M06 functionals elucidated the reactivities of alkynes and Z/E selectivity of cyclodecatriene products in the Ni-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes.
Baran, Phil S +4 more
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Beilstein Journal of Organic Chemistry, 2017 Intramolecular nucleophilic and electrophilic cyclization of N-alkyne-substituted pyrrole esters is described. Efficient routes towards the synthesis of pyrrolopyrazinone, pyrrolotriazinone and pyrrolooxazinone have been developed.
Işıl Yenice +2 more
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3-(3-Nitrophenyl)-1-[4-(prop-2-ynyloxy)phenyl]prop-2-en-1-one
IUCrData, 2022 The structure of the title compound, C18H13NO4, shows that the whole molecule is almost planar but with a dihedral angle between the two phenyl rings of 19.22 (5)°.
Vinaya +6 more
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Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
, 2011 A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
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Bidentate Lewis Acids Derived from o‐Diethynylbenzene with Group 13 and 14 Functions
ChemistryOpen, 2021 Starting from 1,2‐diethynylbenzene, a series of bidentate Lewis acids was prepared by means of hydrometalations, in particular hydrosilylation, hydroboration, hydroalumination and terminal metalation based on group 13 and 14 elements.
Jens Rudlof +5 more
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Reactions of Tetracyclone Molybdenum Complexes with Electrophilic Alkynes: Cyclopentadienone–Alkyne Coupling and Alkyne Coordination [PDF]
Organometallics, 2017 The reactions of the complexes [Mo(CO)2(η4-C4Ph4CO)2] and [Mo(CO)3(NCMe)(η4-C4Ph4CO)] with the alkynes dimethyl acetylenedicarboxylate (DMAD; RC≡CR where R = CO2Me) and methyl propiolate (RC≡CH) have been studied. In the case of DMAD, the initial product is the green carbonyl complex [Mo(CO)(RC≡CR)(η5,σ-C4Ph4COCR═CR)] (3), in which two alkyne molecules
Adams, H. +4 more
openaire +2 more sources
Discovery of TUG-770: a highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist for treatment of type 2 diabetes [PDF]
, 2013 Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and currently attracts high interest as a new target for the treatment of type 2 diabetes.
Blad C. C. +18 more
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