Results 31 to 40 of about 18,841,230 (238)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Haematologica, 2013 Adoptive transfer of ex vivo expanded CD4+CD25+FOXP3+ regulatory T cells is a successful therapy for autoimmune diseases and transplant rejection in experimental models.
Cristiano Scottà +11 more
doaj +1 more source
Post-natal all-trans-retinoic acid biosynthesis [PDF]
, 2020 Generation of the autacoid all-trans-retinoic acid (ATRA) from retinol (vitamin A) relies on a complex metabolon that includes retinol binding-proteins and enzymes from the short-chain dehydrogenase/reductase and aldehyde dehydrogenase gene families. Serum retinol binding-protein delivers all-trans-retinol (vitamin A) from blood to cells through two ...
openaire +5 more sources
Haematologica, 2009 Background In a previous randomized trial, AML HD98B, we showed that administration of all-trans retinoic acid in addition to intensive chemotherapy improved the outcome of older patients with acute myeloid leukemia.
Richard F. Schlenk +19 more
doaj +1 more source
Journal of Lipid Research, 2003 All-trans and 9-cis retinoic acids function as ligands for retinoic acid receptors (RARs and RXRs), which are ligand-dependent transcription factors and play important roles in development and cellular differentiation.
Helene Brodeur +3 more
doaj +1 more source
The effects of All-Trans-Retinoic Acid on the growth of tumor cells
四川大学学报. 自然科学版, 2021 In order to explore the effects of All-Trans-Retinoic Acid (ATRA) on the growth of pancreatic cancer and osteosarcoma cells, this study used a larger span of ATRA concentration to treat pancreatic cancer cells PANC-1 and osteosarcoma cells U2OS and cell ...
LUO Xing-Yong +3 more
doaj
Journal of Lipid Research, 1995 This study was done to examine the intestinal absorption and cleavage of 9-cis-beta-carotene in vivo. A micellar solution, containing either no addition or 10 mumol of 9-cis- or all-trans-beta-carotene, was perfused for 2 h through the upper portion of ...
X. Hébuterne +4 more
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All-trans retinoic acid modulates ORMDL3 expression via transcriptional regulation. [PDF]
PLoS ONE, 2013 All-trans retinoic acid (ATRA) is an active metabolite of Vitamin A, it shows protective effects on asthma, including maintains airway epithelial integrity, inhibits asthma effector cells differentiation, modulates immune response, et al.
Li-Li Zhuang +6 more
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Cells, 2022 Retinoic acid signaling plays an important role in regulating lipid metabolism and inflammation. However, the role of retinoic acid receptor alpha (RARα) in atherosclerosis remains to be determined.
Fathima N. Cassim Bawa +7 more
doaj +1 more source