Results 31 to 40 of about 82,660 (245)
All-Trans-Retinoic-Acid Unmasking Hypercalcemia of Hyperparathyroidism [PDF]
Indian Journal of Hematology and Blood Transfusion, 2015 We present a patient of acute promyelocytic leukaemia managed with all-trans-retinoic-acid and arsenic trioxide who developed hypercalcemia with target organ damage. The patient also was simultaneously discovered to be symptomatic from hyperparathyroidism, which was unmasked after ATRA administration.
Uday, Yanamandra +5 more
openaire +2 more sources
Journal of Lipid Research, 2002 Two mammalian hCYP26A expression systems have been used to analyze the metabolic products of CYP26A. Through the use of extensive HPLC, UV spectroscopy, and liquid chromatography/tandem mass spectrometry (LC-MS/MS) methodology, we have conclusively ...
James V. Chithalen +3 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message This is the first case of a promyelocytic sarcoma diagnosed on pleural effusion and exposed the difficulty of demonstrating a leukemic phase in patients with bone diseases, such as Gorham's disease.
Romain Loyaux +9 more
doaj +1 more source
All trans retinoic acid in acute promyelocytic leukemia [PDF]
Oncogene, 2001 All trans retinoic acid (ATRA) is able to induce complete remission (CR) in almost all patients with acute promyelocytic leukemia (APL) through in vivo differentiation of APL blasts. However, it cannot eliminate the leukemic clone and to be effective must be used in combination with anthracycline-based chemotherapy. Experience accumulated over the last
L, Degos, Z Y, Wang
openaire +2 more sources
Pseudotumor cerebri presenting with visual failure in promyelocytic leukemia: a case report
Journal of Medical Case Reports, 2012 Introduction Pseudotumor cerebri secondary to all-trans retinoic acid in acute promyelocytic leukemia is a reported but rare complication of the therapy. Most cases improve following the discontinuation of all-trans retinoic acid.
Rasul Fahid T +4 more
doaj +1 more source
Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]
, 2015 Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee +6 more
core +2 more sources
All-Trans Retinoic Acid Induces DU145 Cell Cycle Arrest through Cdk5 Activation [PDF]
, 2014 All-trans retinoic acid (ATRA), the active form of vitamin A, plays an important role in the growth arrest of numerous types of cancer cells. It has been indicated that cyclin-dependent kinase 5 (Cdk5) activity can be affected by ATRA treatment.
Chen, Mei-Chih +7 more
core +8 more sources
Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
, 2014 Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
core +2 more sources
Genital vasculitis secondary to all-trans-retinoic-acid [PDF]
BMJ Case Reports, 2016 Acute promyelocytic leukaemia is among the most curable haematological malignancies after the introduction of differentiating agents (arsenic trioxide (ATO) and all-trans-retinoic-acid (ATRA)). Despite excellent cure rates, approaching 85–95% in various series, APL is associated with significant early mortality and morbidity.
Uday, Yanamandra +3 more
openaire +2 more sources
Haematologica, 2009 Background In a previous randomized trial, AML HD98B, we showed that administration of all-trans retinoic acid in addition to intensive chemotherapy improved the outcome of older patients with acute myeloid leukemia.
Richard F. Schlenk +19 more
doaj +1 more source