Results 51 to 60 of about 82,660 (245)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Therapeutic Advances in Hematology, 2021 Some subtypes of acute myeloid leukemia (AML) share morphologic, immunophenotypic, and clinical features of acute promyelocytic leukemia (APL), but lack a PML–RARA (promyelocytic leukemia–retinoic acid receptor alpha) fusion gene.
Xiaoyan Han +7 more
doaj +1 more source
The effect of all-trans retinoic acid on the migration of avian neural crest cells in vitro an in vivo [PDF]
, 2007 Student Number : 9502128Y - MSc dissertation - School of Anatomical Sciences - Faculty of ScienceRetinoic acid, the active metabolite of Vitamin A is known to play a major role in embryonic growth and differentiation during development.
Tshabalala, Vincent Abie Thabiso
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Differentiation enhances Zika virus infection of neuronal brain cells. [PDF]
, 2018 Zika virus (ZIKV) is an emerging, mosquito-borne pathogen associated with a widespread 2015-2016 epidemic in the Western Hemisphere and a proven cause of microcephaly and other fetal brain defects in infants born to infected mothers. ZIKV infections have
Bouquet, Jerome +6 more
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Biology and Life Sciences Forum, 2023 The biological activity of retinoic acid or all-trans retinoic acid (ATRA) is mediated by retinoic receptors, which are ligand-dependent transcription factors that activate genes crucial for cell differentiation.
John Charles Rotondo +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Haematologica, 2012 Background A subset of patients with fludarabine-resistant chronic lymphocytic leukemia has previously been shown to express elevated intracellular levels of the concentrative high-affinity fludarabine transporter hCNT3, without any detectable related ...
Paula X. Fernández-Calotti +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen +15 more
wiley +1 more source
The Genetic Role of Retinoic Acid Receptors in Embryonic Development: Study of Genetic Mutations in Retinoic Acid Receptors, Resulting in Tissue Abnormalities [PDF]
, 2007 Retinoic acid (RA) is a vitamin A derivative that exerts profound influences in vertebrate development and physiology. All-trans RA and 9-cis RA, are important regulators of embryonic development, cellular activity and tissue homeostasis.
Ghaedi, Kamran. +2 more
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