Results 71 to 80 of about 18,841,230 (238)

All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)

, 2012
All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia ...
J Seymour (9880217), John Reynolds (13054194), S Supple (13710667), A Hugman (13710823), J Szer (13404321), C Tiley (13645984), J Taper (13404426), J Moore (6981110), K Bradstock (13710649), J Di Iulio (13710826), A Catalano (13710664), F Firkin (13612084), M Seldon (13710829), M Collins (7710758), P Browett (13710652), R Filshie (13404594), A Grigg (13404300), J Bashford (13710832), K Taylor (9851333), M Hertzberg (13404438), H Iland (13710646)   +20 more
core  

The healing effect of all-trans retinoic acid on epithelial corneal abrasions in rabbits

, 1998
ophthalmology, all-trans retinoic acid, placebo, corneal abrasion ...
Johansen, Sven, Heegaard, Steffen, Prause, J.U., Rask-Pedersen, Eva   +3 more
core   +1 more source

The Effect of All-Trans Retinoic Acid Supplementation to Periodontitis

LINK, 2015
Vitamin A metabolite all-trans retinoic acid (ATRA), regulates periodontal collagen synthesis. Type 1 collagen, main component of periodontium was destroyed in perio-dontitis.
Praptiwi Hanafi, Enik Sulistyowati, Kustiono Kustiono   +2 more
doaj   +1 more source

Functional Characterization of CYP26B1 Short Isoform as a Novel Locus for Obesity in Indigenous Americans From Arizona

Obesity, EarlyView.
ABSTRACT Objective To identify heritable factors that affect BMI among Indigenous Americans, we previously conducted a genome‐wide association study using 7.9 million imputed genetic variants from 6789 participants. This study sought to identify a mechanistic link between variants with the strongest association with BMI and adipocyte metabolism ...
Fehmida Farid Khan, Michael Traurig, Kendrick Freeland, Robert L. Hanson, Paolo Piaggi, Leslie J. Baier   +5 more
wiley   +1 more source

ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion

Nature Communications, 2016
Persistent activation of pancreatic stellate cells (PSCs) can perturb the biomechanical homeostasis of the tumour microenvironment. Here the authors show that all-trans retinoic acid reduces retinoic acid receptor beta dependent-actomyosin contractility ...
Antonios Chronopoulos, Benjamin Robinson, Muge Sarper, Ernesto Cortes, Vera Auernheimer, Dariusz Lachowski, Simon Attwood, Rebeca García, Saba Ghassemi, Ben Fabry, Armando del Río Hernández   +10 more
doaj   +1 more source

Predictive role of vitamin A serum concentration in psoriatic patients treated with IL-17 inhibitors to prevent skin and systemic fungal infections

Journal of Pharmacological Sciences, 2020
The use of biological drugs in psoriasis is replacing traditional therapies due to their specific mechanism and limited side effects. However, the use of Interleukin 17 inhibitors and the modification of its cytokine pathway could favor the risk of ...
Campione Elena, Cosio Terenzio, Lanna Caterina, Mazzilli Sara, Ventura Alessandra, Dika Emi, Gaziano Roberta, Dattola Annunziata, Candi Eleonora, Bianchi Luca   +9 more
doaj   +1 more source

Binding of 9-cis-retinoic acid and all-trans-retinoic acid to retinoic acid receptors alpha, beta, and gamma. Retinoic acid receptor gamma binds all-trans-retinoic acid preferentially over 9-cis-retinoic acid

Journal of Biological Chemistry, 1994
Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.
G, Allenby, R, Janocha, S, Kazmer, J, Speck, J F, Grippo, A A, Levin   +5 more
openaire   +2 more sources

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Fungistatic activity of all-trans retinoic acid against Aspergillus fumigatus and Candida albicans

, 2016
Elena Campione,1 Roberta Gaziano,2 Daniele Marino,2 Augusto Orlandi3 1Department of Dermatology, 2Department of Microbiology, 3Department of Anatomic Pathology, University of Rome Tor Vergata, Rome, Italy Purpose: Fungal infections are a major ...
Orlandi A, Gaziano R, Marino D, Campione E   +3 more
core  

Arsenic trioxide is required in the treatment of newly diagnosed acute promyelocytic leukemia. Analysis of a randomized trial (APL 2006) by the French Belgian Swiss APL group

Haematologica, 2018
In standard-risk acute promyelocytic leukemia, recent results have shown that all-trans retinoic acid plus arsenic trioxide combinations are at least as effective as classical all-trans retinoic acid plus anthracycline-based chemotherapy while being less
Lionel Adès, Xavier Thomas, Agnes Guerci Bresler, Emmanuel Raffoux, Olivier Spertini, Norbert Vey, Tony Marchand, Christian Récher, Arnaud Pigneux, Stephane Girault, Eric Deconinck, Claude Gardin, Olivier Tournilhac, Jean Francois Lambert, Patrice Chevallier, Stephane de Botton, Julie Lejeune, Hervé Dombret, Sylvie Chevret, Pierre Fenaux   +19 more
doaj   +1 more source