Results 31 to 40 of about 7,201 (180)

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Management of Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review

Health Care Science, EarlyView.
The data obtained through this review highlight the lack of global consensus among radiotherapy centers on the best topical treatment for radiodermatitis. It indicates that the choice of treatment depends on professional judgment due to the absence of standardized guidelines, pointing to the need for more robust scientific research to develop effective
Tâmara Taynah Medeiros da Silva, Louise Constancia de Melo Alves Silva, Thatiane Evelyn de Lima Fernandes, Karena Cristina da Silva Leal, Thaís Brunna Maurício Pinheiro, Guilherme Moises Alves Fernandes, Kátia Regina Barros Ribeiro, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas   +8 more
wiley   +1 more source

Allantoin reduces glucotoxicity and lipotoxicity in a type 2 diabetes rat model by modulating the PI3K and MAPK signaling pathways

Heliyon
Objective: The current study aimed to investigate the potential therapeutic impact of allantoin on diabetes produced by a high-fat diet (HFD) and streptozotocin (STZ) in rats.
Yao Zhao, Ming Qiao, Xiaomei Wang, Xinjie Luo, Jianhua Yang, Junping Hu   +5 more
doaj   +1 more source

Immobilization of Allantoinase for the Development of an Optical Biosensor of Oxidative Stress States

Sensors, 2019
Allantoin, the natural end product of purine catabolism in mammals, is non-enzymatically produced from the scavenging of reactive oxygen species through the degradation of uric acid.
Marialaura Marchetti, Luca Ronda, Riccardo Percudani, Stefano Bettati   +3 more
doaj   +1 more source

A Systematic Review and Meta-Analysis of the Association between Uric Acid and Allantoin and Rheumatoid Arthritis

Antioxidants, 2023
Alterations in the circulating concentrations of uric acid and its degradation product, allantoin, might account for the systemic pro-oxidant state and the increased cardiovascular risk in rheumatoid arthritis (RA).
Angelo Zinellu, Arduino A. Mangoni
doaj   +1 more source

CXLIV.—The constitution of allantoin [PDF]

J. Chem. Soc., Trans., 1913
n ...
openaire   +1 more source

Kinetics of allantoin metabolism in sheep [PDF]

British Journal of Nutrition, 2000
The kinetics of allantoin metabolism were studied in rumen-cannulated sheep by means of a single intravenous injection of [4,5-14C]allantoin. The decline in the specific radioactivity of allantoin in plasma following the injection of tracer was best described by a double exponential function, indicating that allantoin moves in and out of two or more ...
L P, Kahn, J V, Nolan
openaire   +2 more sources

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Copaiba oleoresin as a substitute for sodium lasalocid in high‐concentrate diets for lambs: growth performance, ingestive behavior, and metabolic and ruminal parameters

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The indiscriminate and excessive use of ionophore additives has been associated with the emergence of multi‐resistant pathogenic strains and the global spread of antibiotic resistance, raising serious public health concerns. Thus, plant biocompounds have been the focus of several studies aiming to replace ionophore additives in ...
Jéssica Carvalho de Pantoja, Aylpy Renan Dutra Santos, Cristiane Rebouças Barbosa, Carla Giselly Souza, Tatiane Fernandes, Elaine Cristina Pacheco de Oliveira, Marcio Rodrigues de Souza, Fernando Miranda de Vargas Junior   +7 more
wiley   +1 more source

Influence of Tapered‐End and Round‐End Bristle Designs on the Abrasive Enamel Wear Using Toothpastes With High Discrepancies in Abrasiveness

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose The aim of this in vitro study was to investigate the influence of bristle end design of toothbrushes and the relative enamel abrasivity (REA) of used toothpaste on the resulting abrasive enamel wear. Materials and Methods A total of 160 bovine enamel samples were allocated into eight groups (n = 20) and surface topography was recorded
Michelle S. Stübi, Moritz Tanner, Blend Hamza, Leonardo Svellenti, Thomas Attin, Florian J. Wegehaupt   +5 more
wiley   +1 more source