Results 31 to 40 of about 8,873 (215)
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Antioxidants, 2023 Allantoin is an emerging plant metabolite, but its role in conferring drought-induced oxidative stress is still elusive. Therefore, an experiment was devised to explore the role of allantoin (0.5 and 1.0 mM; foliar spray) in rapeseed (Brassica campestris
Md. Rakib Hossain Raihan +4 more
doaj +1 more source
Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective.
Tahereh Komeili Movahhed +3 more
doaj +1 more source
Opposite fates of the purine metabolite allantoin under water and nitrogen limitations in bread wheat [PDF]
, 2019 Key message: Degradation of nitrogen-rich purines is tightly and oppositely regulated under drought and low nitrogen supply in bread wheat. Allantoin is a key target metabolite for improving nitrogen homeostasis under stress.
Erban, A. +15 more
core +2 more sources
Research in Pharmaceutical Sciences, 2021 Background and purpose: Nonalcoholic steatohepatitis (NASH) is considered a common and serious liver disease, which develops into cirrhosis, fibrosis, and even hepatocellular carcinoma.
Zeinab Hamidi-zad +2 more
doaj +1 more source
The In Vitro Wound-Scratch Assay: Applications, Technical Advances, and Limitations in Wound Healing Research. [PDF]
Int Wound JABSTRACT The wound‐scratch assay is a widely used in vitro model for studying collective cell migration, a fundamental process contributing to wound closure and re‐epithelialisation. Owing to its simplicity, low cost, and adaptability, it has become a foundational tool for early‐stage wound‐healing research and therapeutic screening. The assay involves
Molefe PF +3 more
europepmc +2 more sources
The Effect of Allantoin on Chronic Perforation of Rat Tympanic Membrane
, 2021 OBJECTIVES: This study aimed to investigate the effectiveness of topical allantoin application on wound healing in a rat chronic tympanic membrane perforation (TMP) model. METHODS: A chronic TMP model was established with 25 healthy, female, 6-month-old,
Ali Bayram +7 more
core +1 more source
Biovalentia: Biological Research Journal, 2023 Allantoin is a compound contained in comfrey leaves. This research aims to obtain optimal condition parameters of ionic liquid-ultrasound-assisted extraction (IL-UAE) comfrey leaves to attract allantoin compounds. Comfrey leaves are extracted with eight
Andika Purnomo +2 more
doaj +1 more source
Gut Bacterial Species Distinctively Impact Host Purine Metabolites during Aging in Drosophila
iScience, 2020 Summary: Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product
Toshitaka Yamauchi +7 more
doaj +1 more source
SHILLIQ QURT SHILLIQ QAVATI VA ALLANTOIN OQSILI
, 2022 ushbu maqolada shilliq qurt shilliq qavatining muhim tarkibiy qismi hisoblangan allantoin oqsilining kimyoviy formulasi, allantoin oqsilining mo’jizaviy sifatlari va oqsilning kosmetologik ahamiyati haqida ma’lumotlar ...
Diyoraxon Isomiddin qizi Toychiyeva, Ibroxim Raxmonovich Asqarov
core +1 more source