Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino +12 more
wiley +1 more source
Increased risk of IgE-mediated allergies in patients with celiac disease: a case-control study. [PDF]
Azhati A +8 more
europepmc +1 more source
Baseline Serum Tryptase Correlation with Severe Reactions to Allergen and Venom Immunotherapy [PDF]
Aneesh K. Mehta +4 more
openalex +1 more source
Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller +9 more
wiley +1 more source
Evaluation of the Quality and Reliability of ChatGPT-4's Responses on Allergen Immunotherapy Using Validated Instruments for Health Information Quality Assessment. [PDF]
Cherrez-Ojeda I +19 more
europepmc +1 more source
A1.2 - Replicae of Antibodies - Robust Mass-Sensitive Sensors for Allergens and Other Bioanalytes
Franz L. Dickert +4 more
openalex +2 more sources
Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek +7 more
wiley +1 more source
Cross-reactive IgE-binding Proteins from Philippine Allergenic Weeds and Trees Pollen Extracts. [PDF]
Cruz MKDM +7 more
europepmc +1 more source
Heat-treated egg allergens show lower basophil activation: A path toward safer oral immunotherapy. [PDF]
Paolucci M +12 more
europepmc +1 more source

