Results 41 to 50 of about 94,577 (314)

RNA vaccines: The dawn of a new age for tuberculosis?

Human Vaccines & Immunotherapeutics
Since 2019, there has been a growing focus on mRNA vaccines for infectious disease prevention, particularly following the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Junli Li, Dong Liu, Xiaochi Li, Jiazheng Wei, Weixin Du, Aihua Zhao, Miao Xu   +6 more
doaj   +1 more source

Nanoparticle–allergen complexes for allergen immunotherapy

International Journal of Nanomedicine, 2017
Allergen-specific immunotherapy was introduced in clinical settings more than 100 years ago. It remains the only curative approach to treating allergic disorders that ameliorates symptoms, reduces medication costs, and blocks the onset of new sensitizations.
Paolo Colombo, Gabriella Di Felice
openaire   +6 more sources

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Eosinophilic Pneumonia Triggered by Toxocara canis in a Patient with Primary Ciliary Dyskinesia: A Clinical Case Report

Medicina
Primary ciliary dyskinesia (PCD) is a rare genetic disorder that affects the structure and function of cilia, primarily impacting the respiratory system.
Kacper Packi, Wanda Fugiel, Violetta Gołąbek, Alicja Rudek, Agnieszka Śliwińska   +4 more
doaj   +1 more source

Analysis of the Comorbidity of Bronchial Asthma and Allergic Rhinitis by Questionnaire in 10,009 Patients

Allergology International, 2009
Background: Bronchial asthma (BA) and allergic rhinitis (AR) are thought to share a common pathogenesis. However, reports concerning the comorbidity of the two diseases in a large-scaled population are rare in Japan. In the present study, we performed an
Kohei Yamauchi, Gen Tamura, Toru Akasaka, Toshihiko Chiba, Kohei Honda, Motoji Kishi, Hitoshi Kobayashi, Tadayuki Kuronuma, Atsushi Matsubara, Toshio Morikawa, Hiroshi Ogawa, Nobuo Ohta, Masahiko Okada, Masahiro Sasaki, Junpei Saito, Kunio Sano, Morito Satoh, Yoko Shibata, Yoshihiro Takahashi, Shingo Takanashi, Hiroshi Inoue   +20 more
doaj   +1 more source

Occupational Exposure Patterns to Disinfectants and Cleaning Products and Its Association With Asthma Among French Healthcare Workers

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Disinfectants and cleaning products (DCPs) are important asthma risk factors among healthcare workers. However, healthcare work involves heterogenous cleaning tasks and co‐exposure to many chemicals. These multidimensional aspects have rarely been considered.
Bakari Ibrahim, Nicole Le Moual, Guillaume Sit, Marcel Goldberg, Bénédicte Leynaert, Céline Ribet, Nicolas Roche, Raphaëlle Varraso, Marie Zins, Rachel Nadif, Laurent Orsi, Orianne Dumas   +11 more
wiley   +1 more source

Electrochemical Affinity Biosensors Based on Disposable Screen-Printed Electrodes for Detection of Food Allergens

Sensors, 2016
Food allergens are proteins from nuts and tree nuts, fish, shellfish, wheat, soy, eggs or milk which trigger severe adverse reactions in the human body, involving IgE-type antibodies.
Alina Vasilescu, Gilvanda Nunes, Akhtar Hayat, Usman Latif, Jean-Louis Marty   +4 more
doaj   +1 more source

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells

Frontiers in Immunology, 2020
Changing the immune responses to allergens is the cornerstone of allergen immunotherapy. Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative. The major inconveniences of
Ricardo Wesley Alberca-Custodio, Lucas D. Faustino, Eliane Gomes, Fernanda Peixoto Barbosa Nunes, Mirian Krystel de Siqueira, Alexis Labrada, Rafael Ribeiro Almeida, Niels Olsen Saraiva Câmara, Denise Morais da Fonseca, Momtchilo Russo   +9 more
doaj   +1 more source

Outdoor allergens. [PDF]

Environmental Health Perspectives, 2000
Outdoor allergens are an important part of the exposures that lead to allergic disease. Understanding the role of outdoor allergens requires a knowledge of the nature of outdoor allergen-bearing particles, the distributions of their source, and the nature of the aerosols (particle types, sizes, dynamics of concentrations).
Burge, Harriet A., Rogers, Christine Anne   +1 more
openaire   +3 more sources

Biodiversity of the Bacterial and Fungal Microbiome and Associated Inflammatory Cytokine Profile in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Dysbiosis of the bacterial and fungal microbiome has been increasingly implicated in the pathogenesis of chronic rhinosinusitis (CRS). This study explores the relationship between microbiome and mycobiome biodiversity and type 2 (T2) versus non‐type 2 (NT2) inflammation.
Hong‐Ho Yang, Carra A Simpson, Meera Srivastava, Alakesh Bera, Monica Cappelletti, Jeffrey D. Suh, MarileneB. Wang, Daniel M. Beswick, Tom Maxim, Saroj K. Basak, Eri S. Srivatsan, Jakob L. Fischer, Jonathan P Jacobs, Jivianne T. Lee   +13 more
wiley   +1 more source