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What Makes an Allergen an Allergen [PDF]

open access: bronzeAllergy, 1978
In the vocabulary of daily life the term allergen is most often used to indicate the whole substance able to initiate an allergic reaction, such as certain pollens, moulds, house dust mites, animal dander, cow's milk and other inhalants or food items known to trigger immediate or late, hypersensitivity reactions.
Kjell Aas
openalex   +4 more sources

Allergen nomenclature* [PDF]

open access: bronzeJournal of Allergy and Clinical Immunology, 1988
SummaryThis article presents a nomenclature system for allergens which has been officially recommended by the International Union of Immunological Societies (IUIS). The nomenclature is based on proposals of the IUIS Sub‐Committee for Allergen Nomenclature and is applicable to highly purified, well‐characterized allergens and to non‐purified or ...
David G. Marsh   +4 more
openalex   +4 more sources

Immunogenicity of a novel anti-allergic vaccine based on house dust mite purified allergens and a combination adjuvant in a murine prophylactic model

open access: yesFrontiers in Allergy, 2022
The outer-membrane-derived proteoliposome (PL) of Neisseria meningitidis has been reported as a potent vaccine adjuvant, inducing a Th1-skewed response.
Wendy Ramírez   +6 more
doaj   +1 more source

Analysis of skin prick test results for 224 patients with eczema [PDF]

open access: yesE3S Web of Conferences, 2020
Objective: To understand the common inhalant allergens and food allergens and their characteristics on patients with eczema in Chongqing area. Method: Skin prick tests of common inhalant allergens and food allergens were performed on 224 patients with ...
Hongzhi Gu   +3 more
doaj   +1 more source

Impact of oligomerization on the allergenicity of allergens

open access: yesClinical and Molecular Allergy, 2022
AbstractType I hypersensitivity (allergic reaction) is an unsuitable or overreactive immune response to an allergen due to cross-link immunoglobulin E (IgE) antibodies bound to its high-affinity IgE receptors (FcεRIs) on effector cells. It is needless to say that at least two epitopes on allergens are required to the successful and effective cross ...
Amin Moradi Hasan-Abad   +5 more
openaire   +3 more sources

Erroneous Belief that Digestive Stability Predicts Allergenicity May Lead to Greater Risk for Novel Food Proteins

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
There continues to be an erroneous belief that allergens (especially food allergens) are more resistant to gastrointestinal digestion than non-allergens.
Rod A. Herman, Jason M. Roper
doaj   +1 more source

pH-dependent structural diversity of profilin allergens determines thermal stability

open access: yesFrontiers in Allergy, 2022
The family of profilin allergens is a common class of proteins found in plants, viruses and various eukaryotes including mammals. Profilins are characterized by an evolutionary conserved structural fold, which is responsible for their cross-reactive ...
Florian Hofer   +5 more
doaj   +1 more source

Allergy vaccines for specific immunotherapy

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2021
Allergen-specific immunotherapy (ASIT) has been used for more than a hundred years to treat patients with IgEmediated allergic diseases. The most common allergens have been obtained using molecular cloning technology in the past two decades.
S. Yu. Petrova   +3 more
doaj   +1 more source

Investigation of the allergens in 2,316 children with allergic rhinitis from Guangdong, China

open access: yesFrontiers in Pediatrics, 2022
Allergic rhinitis (AR) is one of the popular childhood diseases, bringing physical and metal burdens to the children and their families. The study was performed to detect common allergens eliciting AR in children, to investigate the prevalence of ...
Nannan Zhang   +8 more
doaj   +1 more source

En route to personalized medicine: uncovering distinct IgE reactivity pattern to house dust mite components in Brazilian and Austrian allergic patients

open access: yesClinical and Translational Allergy, 2021
Aim Molecular sensitization profile analyses of allergic individuals to the house dust mites (HDM) Blomia tropicalis and Dermatophagoides pteronyssinus from Brazil and Austria, in the attempt to comprehend the individual contribution of the molecular ...
Carina S. Pinheiro   +7 more
doaj   +1 more source

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