Results 121 to 130 of about 936,865 (297)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Lactiplantibacillusplantarum APsulloc331261 (GTB1™) promotes butyrate production to suppress mucin hypersecretion in a murine allergic airway inflammation model

Frontiers in Microbiology
IntroductionAllergic airway diseases are one of the serious health problems in worldwide and allergic airway inflammation is a prerequisite led to the exacerbated situation such as mucus hypersecretion, epithelial barrier damage and microbiota dysbiosis.
Hye-Shin Kim, Hye-Shin Kim, Bobae Kim, Wilhelm H. Holzapfel, Wilhelm H. Holzapfel, Hyeji Kang   +5 more
doaj   +1 more source

Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma

Frontiers in Immunology, 2019
Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Kentaro Fujiwara, Tomohito Okano, Hajime Fujimoto, Kentaro Asayama, Atsuro Takeshita, Atsuro Takeshita, Taro Yasuma, Taro Yasuma, Kota Nishihama, Ryo Inoue, Liqiang Qin, Yoshiyuki Takei, Osamu Taguchi, Esteban C. Gabazza   +17 more
doaj   +1 more source

Treatment With the Shaker Head‐Lift Exercise in Head and Neck Cancer Patients With Radiation‐Induced Dysphagia: 12‐Month Results on Swallowing Function From a Randomized, Controlled Trial

Head &Neck, EarlyView.
ABSTRACT Background Dysphagia is a common side‐effect after radiotherapy in head and neck cancer patients. This randomized study aimed to evaluate the effect of the shaker head‐lift exercise (HLE) after 12 months with flexible endoscopic evaluation of swallowing (FEES). Methods Patients were randomly assigned to the intervention (n = 30) or the control
Signe Rödseth Smith, Caterina Finizia, Kerstin Petersson, Lisa Tuomi   +3 more
wiley   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou, Pooja D. Reddy, Purva H. Rumde, Mary L. Klem, Sagar G. Kansara, Oldrich Virag, Yvonne M. Mowery, Nicole N. Scheff, Matthew E. Spector, Shaum Sridharan, Marci L. Nilsen, Kevin J. Contrera   +11 more
wiley   +1 more source

2215

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: Allergic asthma is a chronic lung disease driven by inappropriate inflammatory responses against inhaled allergens. Neuropilin-2 (NRP2) is a pleiotropic transmembrane receptor expressed in the lung, but its role in allergic ...
Timothy P. Moran, Robert M. Immormino, Hideki Nakano, David Peden, Donald N. Cook   +4 more
doaj   +1 more source

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Steffen Kunzmann, Roderich Laug, Laug, Roderich, Norbert Schütze, Krump-Konvalinkova, Vera, Boris W Kramer, Vera Krump-Konvalinkova, Kramer, Boris W., Markus Fehrholz, Schütze, Norbert, Kunzmann, Steffen, Schuetze, Norbert, Fehrholz, Markus, Speer, Christian P., Christian P Speer   +14 more
core   +2 more sources

Twelve‐Month Outcomes of a Preventive Dysphagia Intervention in Patients With Head and Neck Cancer—A Randomized Study

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐associated dysphagia is common after radiotherapy for head and neck cancer and may occur early or years later. The effect of preventive exercises might be undermined by poor adherence. Aim To evaluate the effect of a simple preventive exercise protocol on swallowing function up to 12 months after radiotherapy.
Kerstin Petersson, Signe Rödseth Smith, Charlotte Johansson‐Malmeling, Caterina Finizia, Lisa Tuomi   +4 more
wiley   +1 more source

Risk factors for atopic and non-atopic asthma in a rural area of Ecuador [PDF]

, 2010
Background: Asthma has emerged as an important public health problem of urban populations in Latin America. Epidemiological data suggest that a minority of asthma cases in Latin America may be associated with allergic sensitisation and that other ...
Oviedo, G, Erazo, S, Barreto, ML, Quinzo, I, Moncayo, AL, Fiaccone, RL, Vaca, M, Cooper, PJ, Chico, ME   +8 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source