Results 41 to 50 of about 256,813 (405)

Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]

, 2017
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M, Chiller, Tom M, DiPersio, John, Dubberke, Erik R, Fraser, Victoria J, Olsen, Margaret A, Reske, Kimberly A, Seiler, Sondra, Silveira, Fernanda P   +8 more
core   +2 more sources

Clonal Dominance and Transplantation Dynamics in Hematopoietic Stem Cell Compartments [PDF]

PLoS Comput Biol 13(10): e1005803 (2017), 2017
Hematopoietic stem cells in mammals are known to reside mostly in the bone marrow, but also transitively passage in small numbers in the blood. Experimental findings have suggested that they exist in a dynamic equilibrium, continuously migrating between these two compartments.
arxiv   +1 more source

Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation. [PDF]

, 2020
Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients, and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit ...
Akard, Luke, Chemaly, Roy, Christoph, Sandra, Gerbitz, Armin, Hiemenz, John, Holler, Ernst, Hwang, William YK, Jang, Junho, Koh, Liang Piu, Lee, Dong-Gun, Logan, Aaron C, Long, Gwynn, Maertens, Johan, Mielke, Stephan, Pertel, Peter, Ramachandra, Sangana, Segal, Florencia, Smith, Kristin, Tang, Jih-Luh, Wang, Po-Nan, Winkler, Julia, Yeh, Su-Peng, Yeo, Adeline   +22 more
core   +3 more sources

Plasticity after allogeneic hematopoietic stem cell transplantation [PDF]

bchm, 2008
Abstract The postulated almost unlimited potential of transplanted hematopoietic stem cells (HSCs) to transdifferentiate into cell types that do not belong to the hematopoietic system denotes a complete paradigm shift of the hierarchical hemopoietic tree.
Rovó, A., Gratwohl, A.
openaire   +6 more sources

Optimized therapeutic strategy for patients with refractory or relapsed acute myeloid leukemia: long‐term clinical outcomes and health‐related quality of life assessment

Cancer Communications, Volume 42, Issue 12, Page 1387-1402, December 2022., 2022
Abstract Background Patients with refractory or relapsed acute myeloid leukemia (AML) have poor survival, necessitating the exploration of optimized therapeutic strategy. Here, we aimed to investigate clinical outcomes and health‐related quality of life (HR‐QoL) after total therapy, which included allogeneic hematopoietic stem cell transplantation ...
Chen‐hua Yan, Yu Wang, Yu‐qian Sun, Yi‐fei Cheng, Xiao‐dong Mo, Feng‐rong Wang, Yu‐hong Chen, Yuan‐yuan Zhang, Ting‐ting Han, Huan Chen, Lan‐ping Xu, Xiao‐hui Zhang, Kai‐yan Liu, Xiao‐jun Huang   +13 more
wiley   +1 more source

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao, Guenther, Wolfgang, Kolb, Hans-Jochem, Ledderose, Georg, Roskrow, Marie, Schleuning, Michael, Schmid, Christoph, Weber, Martin, Woiciechowski, Anja   +8 more
core   +1 more source

J‐SUPPORT research policy for oral mucositis associated with cancer treatment

Cancer Medicine, Volume 11, Issue 24, Page 4816-4829, December 2022., 2022
Abstract Background Oral mucositis is one of the main areas of research in supportive and palliative care of cancer patients. However, the methodology of prospective clinical trials on oral mucositis has not been established, despite its uniqueness.
Tomoya Yokota, Takao Ueno, Yoshihiko Soga, Hiroto Ishiki, Yasuhito Uezono, Takehiko Mori, Sadamoto Zenda, Yosuke Uchitomi   +7 more
wiley   +1 more source

Costs of Allogeneic Hematopoietic Stem Cell Transplantation

Transplantation, 2006
This study aims to determine the total costs after allogeneic hematopoietic stem cell transplantation (ASCT) and factors associated with increases or decreases in costs.We collected all in- and outpatient costs during 5 years in 93 patients who had undergone ASCT in 1998 and 1999 at our unit.
Ann Gardulf, Olle Ringdén, Olle Ringdén, Mats Remberger, Britt-Marie Svahn, O. Alvin   +5 more
openaire   +5 more sources

Autologous Graft-versus-Tumor Effect: Reality or Fiction?

Advances in Hematology, 2016
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell ...
Luis F. Porrata
doaj   +1 more source

Retrospective Study of Incidence and Prognostic Significance of Eosinophilia after Allogeneic Hematopoietic Stem Cell Transplantation: Influence of Corticosteroid Therapy

Turkish Journal of Hematology, 2016
Objective: The clinical significance of eosinophilia after allogeneic hematopoietic stem cell transplantation is controversial. This study aimed to retrospectively study the impact of eosinophilia on the outcome of allogeneic hematopoietic stem cell ...
Wataru Yamamoto, Eriko Ogusa, Kenji Matsumoto, Atsuo Maruta, Yoshiaki Ishigatsubo, Heiwa Kanamori   +5 more
doaj   +1 more source