Results 31 to 40 of about 415,260 (411)

Respiratory Virus Infections in Hematopoietic Cell Transplant Recipients

Frontiers in Microbiology, 2019
Highly immunocompromised pediatric and adult hematopoietic cell transplant (HCT) recipients frequently experience respiratory infections caused by viruses that are less virulent in immunocompetent individuals. Most of these infections, with the exception
Cécile Pochon, Sebastian Voigt, Sebastian Voigt   +2 more
doaj   +1 more source

Non-infectious pulmonary complications of hematopoietic stem cell transplantation [PDF]

, 2014
Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood.
Baloglu, Orkun, McArthur, Jennifer, Rowan, Courtney   +2 more
core   +1 more source

KRAS RENAISSANCE(S) in Tumor Infiltrating B Cells in Pancreatic Cancer

Frontiers in Oncology, 2018
KRAS is a driver mutation for malignant transformation. It is found in 30% of all cancers and in 90% of pancreatic cancers. The identification of small molecules selectively inhibiting KRAS mutants has been challenging, yet mutant KRAS has recently been ...
Qingda Meng, Davide Valentini, Martin Rao, Markus Maeurer, Markus Maeurer   +4 more
doaj   +1 more source

State-of-the-art review: allogeneic stem cell transplantation for myelofibrosis in 2019

Haematologica, 2019
Advances in understanding the pathogenesis and molecular landscape of myelofibrosis have occurred over the last decade. Treating physicians now have access to an ever-evolving armamentarium of novel agents to treat patients, although allogeneic ...
D. Mclornan, I. Yakoub-Agha, M. Robin, Y. Chalandon, C. Harrison, N. Kroger   +5 more
semanticscholar   +1 more source

Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis

International Journal of Infectious Diseases, 2015
The nature and longevity of the T-cell response directed against Mycobacterium tuberculosis (MTB) are important for effective pathogen containment. We analyzed ex vivo the nature of MTB antigen-specific T-cell responses directed against the MTB secreted ...
Rebecca Axelsson-Robertson, Ji Hyeon Ju, Ho-Youn Kim, Alimuddin Zumla, Markus Maeurer   +4 more
doaj   +1 more source

Allogeneic Stem Cell Transplantation for Myelofibrosis in 2012 [PDF]

British Journal of Haematology, 2012
SummaryMyelofibrosis (MF) is a heterogeneous disease for which long‐term, effective medical therapeutic options are currently limited. The role of allogeneic haematopoietic stem cell transplant (AHSCT) in this population, many of whom are elderly, often provides a challenge with regard to the identification of suitable candidates, timing of ...
McLornan, Donal, Mead, Adam J., Jackson, Graham, Harrison, Claire   +3 more
openaire   +6 more sources

Role of allogeneic stem cell transplantation in adult patients with Ph-negative acute lymphoblastic leukemia.

Blood, 2015
Because a pediatric-inspired Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) protocol yielded a markedly improved outcome in adults with Philadelphia chromosome-negative ALL, we aimed to reassess the role of allogeneic stem cell ...
N. Dhédin, A. Huynh, S. Maury, R. Tabrizi, K. Beldjord, V. Asnafi, X. Thomas, P. Chevallier, S. Nguyen, V. Coiteux, J. Bourhis, Y. Hichri, M. Escoffre-barbe, O. Reman, C. Graux, Y. Chalandon, D. Blaise, U. Schanz, V. Lheritier, J. Cahn, H. Dombret, N. Ifrah   +21 more
semanticscholar   +1 more source

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren’s syndrome using high-content peptide microarrays

International Journal of Infectious Diseases, 2017
Introduction: Sarcoidosis is considered an idiopathic granulomatous disease, although similar immunological and clinical features with tuberculosis (TB) suggest mycobacterial involvement in its pathogenesis.
Giovanni Ferrara, Davide Valentini, Martin Rao, Jan Wahlström, Johan Grunewald, Lars-Olof Larsson, Susanna Brighenti, Ernest Dodoo, Alimuddin Zumla, Markus Maeurer   +9 more
doaj   +1 more source

The efficacy and safety of allogeneic stem cell transplantation in Mevalonate Kinase Deficiency

Pediatric Rheumatology Online Journal, 2022
Objectives Mevalonate kinase deficiency (MKD) is a rare autoinflammatory syndrome. Several reports have described allogeneic hematopoietic stem cell transplantation in severely affected patients, sometimes with promising results.
Jerold Jeyaratnam, Maura Faraci, Andrew R. Gennery, Katarzyna Drabko, Mattia Algeri, Akira Morimoto, Tiarlan Sirait, Arjan C. Lankester, Michael Albert, Benedicte Neven, Joost Frenkel, on behalf of the EBMT Inborn Errors Working Party   +11 more
doaj   +1 more source

Allogeneic hematopoietic cell transplantation as curative therapy for patients with non-Hodgkin lymphoma: Increasingly successful application to older patients [PDF]

, 2016
Non-Hodgkin lymphoma (NHL) constitutes a collection of lymphoproliferative disorders with widely varying biological, histological, and clinical features.
Bredeson, Christopher, Cohen, Jonathon B, Costa, Luciano J, Evens, Andrew M, Fenske, Timothy S, Hamadani, Mehdi, Hamlin, Paul A, Kahl, Brad S, Lazarus, Hillard M, Petersdorf, Effie   +9 more
core   +2 more sources