Results 11 to 20 of about 10,210 (217)

Emergence of red blood cell alloantibodies and transfusion management in patients with warm autoantibodies at a tertiary care centre in British Columbia, Canada. [PDF]

open access: yesVox Sang
Abstract Background and Objectives The presence of warm autoantibodies (WAAs) complicates pre‐transfusion and compatibility testing. Despite attempts to provide antigen‐matched red blood cells (RBCs), the risk of alloimmunization remains. Rates of alloimmunization and indications for transfusion were reviewed to streamline testing and RBC provision ...
Hutspardol S   +8 more
europepmc   +2 more sources

Pathophysiology of Alloimmunization [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2019
<b><i>Introduction:</i></b> Alloimmunization is caused by exposure to erythrocytes from a donor that expresses blood group antigens other than those of the recipient and is related to processes that alter the balance of the immune system. Knowing the pathophysiology of alloimmunization process is essential to understand clinical
Rubiraida, Molina-Aguilar   +4 more
openaire   +2 more sources

A Conceptual Framework for Optimizing Blood Matching Strategies: Balancing Patient Complications Against Total Costs Incurred

open access: yesFrontiers in Medicine, 2018
Alloimmunization is currently the most frequent adverse blood transfusion event. Whilst completely matched donor blood would nullify the alloimmunization risk, this is practically infeasible.
Joost H. J. van Sambeeck   +16 more
doaj   +1 more source

Alloimmunization to minor red cell antigen leading to massive hemolysis in newly diagnosed thalassemia intermedia

open access: yesGlobal Journal of Transfusion Medicine, 2021
Alloimmunization to red cell antigens is a taxing complication of thalassemia major and intermedia patients who receive routine blood transfusions. The data on alloimmunization in beta-thalassemia are sparse from developing countries.
Satyam Arora   +3 more
doaj   +1 more source

Micromanaging alloimmunity [PDF]

open access: yesJournal of Clinical Investigation, 2016
Increasing evidence indicates that microbes have a large influence on immune function. Previous studies have linked pathogenic microorganisms with decreased allograft tolerance and subsequent rejection. In this issue of the JCI, Lei and colleagues demonstrate that commensal organisms also influence the host response to allograft transplantation.
openaire   +2 more sources

Red blood cell alloimmunization in patients with sickle cell disease in Turkey: a single center retrospective cohort study

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Purpose: We aimed to investigate erythrocyte alloimmunization frequency and related factors in our region where SCD is common. Material and Methods: This study was planned as a single center, cross-sectional and retrospective cohort study. A total of 216
Soner Solmaz   +10 more
doaj   +1 more source

The Rh blood group system and its role in alloimmunization rate among sickle cell disease and sickle thalassemia patients in Iran

open access: yesMolecular Genetics & Genomic Medicine, 2021
Introduction The alloimmunization following blood transfusion can be life‐threatening. The Rh alloantibodies are one of the most common causes contributing to alloimmunization.
Mohammad Ali Jalali Far   +4 more
doaj   +1 more source

Stillbirth Classification-Developing an International Consensus for Research Executive Summary of a National Institute of Child Health and Human Development Workshop [PDF]

open access: yes, 2009
Stillbirth is a major obstetric complication, with 3.2 million stillbirths worldwide and 26,000 stillbirths in the United States every year. The Eunice Kennedy Shriver National Institute of Child Health and Human Development held a workshop from October ...
Erwich, Jan Jaap H. M.   +13 more
core   +6 more sources

Storage-Induced Platelet Apoptosis Is a Potential Risk Factor for Alloimmunization Upon Platelet Transfusion

open access: yesFrontiers in Immunology, 2018
Platelet transfusion can elicit alloimmune responses leading to alloantibody formation against donor-specific polymorphic residues, ultimately resulting in platelet transfusion refractoriness.
Anno Saris   +10 more
doaj   +1 more source

Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]

open access: yes, 1989
Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ   +5 more
core   +1 more source

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