Results 11 to 20 of about 12,433 (252)

Impact of Isovolemic Hemodilution-Red Cell Exchange on Health-Related Quality of Life in Patients With Sickle Cell Disease: A Pilot Study. [PDF]

J Clin Apher
ABSTRACT Sickle cell disease (SCD) negatively affects health‐related quality of life (HRQoL). Isovolemic hemodilution (IHD) red‐cell exchange (RCE) is being increasingly used to treat SCD‐related complications, but its impact on HRQoL has not been characterized.
Murray A, Sidhu D, Rydz N, Goodyear D, Uminski K.   +4 more
europepmc   +2 more sources

FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization

Frontiers in Immunology, 2022
Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly, anti-D fails in some cases and some monoclonal anti-D preparations paradoxically enhances ...
Annie Qiu, Anabel Miller, Flavia Dei Zotti, Manjula Santhanakrishnan, Jeanne E. Hendrickson, Maria Tredicine, Sean R. Stowell, Chance John Luckey, James C. Zimring, James C. Zimring, Krystalyn E. Hudson   +10 more
doaj   +1 more source

Alloimmunization to erythrocyte antigens in patients receiving multiple blood transfusions: Clinico-immunohematological and demographic risk factors and impact of extended red cell phenotyping

Global Journal of Transfusion Medicine, 2021
Background and Objectives: The risk of red blood cell (RBC) alloimmunization is always a concern for multi-transfused patients. Various factors have been found to be associated with alloimmunization. Alloimmunization rates were reported from 4% to 50%, 1.
Sudipta Sekhar Das, Rathindra Nath Biswas, Mahammad Safi, Rafique Uz Zaman   +3 more
doaj   +1 more source

Red Blood Cell Alloimmunization and Its Associated Factors among Chronic Liver Disease Patients in a Teaching Hospital in Northeastern Malaysia

Diagnostics, 2023
Red blood cell (RBC) alloimmunization is an important complication of blood transfusion. Variations in the frequency of alloimmunization have been noted among different patient populations. We aimed to determine the prevalence of RBC alloimmunization and
Siti Zaleha S. Abdullah, Mohd Nazri Hassan, Marini Ramli, Marne Abdullah, Noor Haslina Mohd Noor   +4 more
doaj   +1 more source

Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]

, 2020
BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric, Elkind, Jae, Morris, Gerald P, Ostberg-Braun, Oscar, Silva Enciso, Jorge, Sobczyk, Juliana   +5 more
core   +1 more source

Red Blood Cell Alloimmunization and Autoimmunization in Blood Transfusion-Dependent Sickle Cell Disease and β-Thalassemia Patients in Al-Ahsa Region, Saudi Arabia

Anemia, 2023
Introduction. The risk of developing transfusion-related complications, especially alloimmunization, is an ongoing concern for transfusion-dependent patients.
Fahd A. Kuriri, Abdulrahman Ahmed, Fehaid Alanazi, Fahad Alhumud, Mohammed Ageeli Hakami, Osama Atiatalla Babiker Ahmed   +5 more
doaj   +1 more source

Pathophysiology of Alloimmunization [PDF]

Transfusion Medicine and Hemotherapy, 2019
<b><i>Introduction:</i></b> Alloimmunization is caused by exposure to erythrocytes from a donor that expresses blood group antigens other than those of the recipient and is related to processes that alter the balance of the immune system. Knowing the pathophysiology of alloimmunization process is essential to understand clinical
Rubiraida, Molina-Aguilar, Soledad, Gómez-Ruiz, Jorge, Vela-Ojeda, Laura Arcelia, Montiel-Cervantes, Elba, Reyes-Maldonado   +4 more
openaire   +2 more sources

Alloimmunization to minor red cell antigen leading to massive hemolysis in newly diagnosed thalassemia intermedia

Global Journal of Transfusion Medicine, 2021
Alloimmunization to red cell antigens is a taxing complication of thalassemia major and intermedia patients who receive routine blood transfusions. The data on alloimmunization in beta-thalassemia are sparse from developing countries.
Satyam Arora, Ravi Shankar, Seema Dua, Nita Radhakrishnan   +3 more
doaj   +1 more source

A Conceptual Framework for Optimizing Blood Matching Strategies: Balancing Patient Complications Against Total Costs Incurred

Frontiers in Medicine, 2018
Alloimmunization is currently the most frequent adverse blood transfusion event. Whilst completely matched donor blood would nullify the alloimmunization risk, this is practically infeasible.
Joost H. J. van Sambeeck, Joost H. J. van Sambeeck, Puck D. de Wit, Jessie Luken, Barbera Veldhuisen, Barbera Veldhuisen, Katja van den Hurk, Anne van Dongen, Maria M. W. Koopman, Marian G. J. van Kraaij, Marian G. J. van Kraaij, Marian G. J. van Kraaij, C. Ellen van der Schoot, Henk Schonewille, Wim L. A. M. de Kort, Wim L. A. M. de Kort, Mart P. Janssen   +16 more
doaj   +1 more source

Micromanaging alloimmunity [PDF]

Journal of Clinical Investigation, 2016
Increasing evidence indicates that microbes have a large influence on immune function. Previous studies have linked pathogenic microorganisms with decreased allograft tolerance and subsequent rejection. In this issue of the JCI, Lei and colleagues demonstrate that commensal organisms also influence the host response to allograft transplantation.
openaire   +2 more sources