Use of an anti‐D‐alloimmunization kinetics model to correct the interval censored D‐alloimmunization rate following red blood cell transfusions [PDF]
Transfusion, Volume 65, Issue S1, Page S304-S312, May 2025.Abstract Introduction The rate of D‐alloimmunization amongst RhD‐negative recipients of RhD‐positive red blood cell (RBC) transfusions is not certain. Recipients with a short duration between the index RhD‐positive transfusion and the last antibody detection test that did not show anti‐D might become D‐alloimmunized in the future.
Emil Ainsworth Jochumsen +6 more
wiley +2 more sources
A spleen is required for antibody mediated immune enhancement but not for RBC clearance or antigen‐modulation in mice [PDF]
Transfusion, Volume 65, Issue 3, Page 453-458, March 2025.Abstract Background IgG against alloantigens on transfused RBC can lead to antibody‐mediated immune enhancement (AMIE). AMIE has properties not found in other forms of alloimmunization, including rapid clearance of RBCs, a requirement for Fc‐gamma receptors on dendritic cells, and no dependence on IFNAR.
Ariel M. Hay, Arijita Jash
wiley +2 more sources
An in silico simulation of the frequency of administering HLA‐incompatible low titer group O whole blood units when the donor pool includes unscreened female donors [PDF]
Transfusion, Volume 65, Issue S1, Page S227-S236, May 2025.Abstract Background As low titer group O whole blood (LTOWB) increases in popularity, blood centers are finding innovative ways of maintaining the supply. One potential way is collecting LTOWB from parous female donors without testing for HLA antibodies.
Mark H. Yazer +5 more
wiley +2 more sources
A prehospital protocol for transfusion of low‐titer O‐positive whole blood in patients with hemorrhagic shock in Los Angeles County: Modeling the risk of hemolytic disease of the fetus and newborn [PDF]
Transfusion, Volume 65, Issue S1, Page S313-S319, May 2025.Abstract Background The Los Angeles Development and Rapid Operationalization of Prehospital Blood (LA‐DROP) pilot will protocolize prehospital administration of low titer O‐positive whole blood (LTO + WB) to patients with hemorrhagic shock in Los Angeles County (LAC).
Kelsey Wilhelm +5 more
wiley +2 more sources
Transfusing selected RhD negative patients with RhD positive packed red cell concentrates resulted in lower frequency of anti‐D development and saved almost two thousand RhD negative concentrates during 5 years [PDF]
Transfusion Medicine, Volume 35, Issue 2, Page 138-143, April 2025.Abstract Background The Blood Bank at Oslo University Hospital implements restrictions when the stocks of blood groups O and A RhD negative packed red blood cell concentrates (PRBCCs) drop below 60 units due to high demand and low donor availability. Restrictions entail transfusing RhD negative male patients and women >50 years with RhD positive units,
Inger Margit Alm +2 more
wiley +2 more sources
Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]
, 2020 BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric +5 more
core +1 more source
The changing trend of alloimmunization in antenatal females: experience from a tertiary care centre in north-western India [PDF]
, 2021 Background: Haemolytic disease of the foetus and new-born (HDFN) is a major concern during the antenatal period, especially in countries with low human development index (HDI). The guidelines for antenatal screening and management significantly vary from
Dubey, Rounak +3 more
core +2 more sources
Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]
, 1989 Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ +5 more
core +1 more source
Leucoreduction of blood components. an effective way to increase blood safety? [PDF]
, 2015 Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria +6 more
core +1 more source
Red cell antibody problems in 1000 liver transplants [PDF]
, 1989 Liver transplant patients frequently require large amounts of blood. The frequency and nature of their red cell (RBC) antibody problems were examined. Records were reviewed in 496 adults and 286 children undergoing 1000 consecutive transplants.
Cornell, FW +5 more
core +1 more source