Results 101 to 110 of about 61,179 (292)

Development of Non-Genetic Risk Stratification Model of Severe Allopurinol Hypersensitivity (NoG-ALLOH Score): A Multicenter Study in Thailand

Journal of Clinical Rheumatology and Immunology
Background The side effect of allopurinol was severe allopurinol hypersensitivity (SAH). There are two major causes including genetic risk factor, HLA-B*58:01 and non-genetic risk factors including female, old age, renal impairment, inadequate starting ...
Patapong Towiwat, Suppachai Lawanaskol, Wichittra Tassaneeyakul, Chonlaphat Sukasem, Niwat Saksit, Nontaya Nakkam, Duangkamon Poolpun, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Worawit Louthrenoo   +10 more
doaj   +1 more source

Interventions for preventing oral mucositis for patients with cancer receiving treatment [PDF]

, 2003
Background: Treatment of cancer with chemotherapy is becoming increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them ...
Bryan, Gemma, Clarkson, Jan E., Furness, Susan, Glenny, Anne-Marie, Khalid, Tasneem, Littlewood, Anne, McCabe, Martin G., Meyer, Stefan, Worthington, Helen V.   +8 more
core   +3 more sources

Age disparities in SGLT2 inhibitor prescription among people with type 2 diabetes: The role of frailty and sex

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Older adults with type 2 diabetes (T2DM) are less likely to receive sodium–glucose cotransporter‐2 (SGLT2) inhibitors, despite their proven cardio‐renal benefits and safety. Whether this age‐related gap is driven by frailty, sex, or other factors remains unclear.
Changyuan Yang, Petra Denig, Lynne Chepulis, Ryan G. Paul, Jung‐Im Shin, Ron T. Gansevoort, Priya Vart   +6 more
wiley   +1 more source

Severe cutaneous adverse drug reaction as a consequence of Allopurinol: The importance of HLA B58:01 testing [PDF]

, 2020
Keshav Poddar, Leslie Cler
openalex   +1 more source

Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]

, 2015
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Abooali, Maryam, Berger, Steffen M., Casely-Hayford, Maxwell A., Fasler-Kan, Elizaveta, Gibbs, Bernhard F., Gonçalves Silva, Isabel, Prokhorov, Alexandr, Sumbayev, Vadim V., Yasinska, Inna M.   +8 more
core   +3 more sources

Challenges of Parents While Providing Complex Medical Care at Home to Children With Cancer: A Cross‐Sectional Convergent Mixed Methods Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore challenges parents of children with cancer encounter while providing complex medical care at home. Methods Design: Cross‐sectional convergent mixed‐methods study. Instruments: Questionnaire and open interviews that mirrored and complemented each other.
Rachel Klausner Shyman, Sveta Roberman, Gal Goldstein, Sabaa Masarwe, Amy Solnica, Rachel Yaffa Zisk‐Rony   +5 more
wiley   +1 more source

Allopurinol: Sorrow to the marrow

Journal of Family Medicine and Primary Care, 2020
Allopurinol is a xanthine oxidase inhibitor used in management of chronic gout. It acts by reducing the amount of uric acid by inhibiting purine metabolism.
U R Raaju, Siddharth Gosavi, K Sriharsha
doaj   +1 more source

Allopurinol-Induced DRESS and Neosensitization to Thalidomide: Complex Management and Diagnosis in a Patient With Multiple Myeloma [PDF]

, 2022
Francisca Vílchez‐Sánchez, José Manuel Busto Leis, Elena Sendagorta, Elena Ramı́rez, Ana Fiandor, Teresa Bellón, Teresa de Soto Álvarez, H Sánchez Ocando, R Heredia Revuelto, Rosario Cabañas   +9 more
openalex   +1 more source

Severe Cutaneous Adverse Drug Reactions Associated with Allopurinol: An Analysis of Spontaneous Reporting System in Southern Italy

Drugs - Real World Outcomes, 2019
Background Allopurinol can induce severe cutaneous adverse reactions (SCARs), including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).
C. Scavone, C. Di Mauro, R. Ruggiero, F. Bernardi, U. Trama, M. Aiezza, C. Rafaniello, A. Capuano   +7 more
semanticscholar   +1 more source

Recent finding and new technologies in nephrolithiasis: a review of the recent literature [PDF]

, 2013
This review summarizes recent literature on advances regarding renal and ureteral calculi, with particular focus in areas of recent advances in the overall field of urolithiasis.
Bove P, Finazzi Agrò E, Kim FJ, Miano R, Micali S, Rosa M, Usai P   +6 more
core   +1 more source