Results 111 to 120 of about 46,519 (250)

Allopurinol-Induced DRESS and Neosensitization to Thalidomide: Complex Management and Diagnosis in a Patient With Multiple Myeloma [PDF]

, 2022
Francisca Vílchez‐Sánchez, José Manuel Busto Leis, Elena Sendagorta, Elena Ramı́rez, Ana Fiandor, Teresa Bellón, Teresa de Soto Álvarez, H Sánchez Ocando, R Heredia Revuelto, Rosario Cabañas   +9 more
openalex   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

Randomized Controlled Trial of Herbal Extracts (Eugenia polyantha, Apium graveolens, Nigella sativa) and Allopurinol Effect on Serum Uric Acid, Urinary Uric Acid and High Sensitivity C-Reactive Protein Levels in Subject with Hyperuricemia

Indonesian Journal of Rheumatology, 2019
Background: Eugenia polyantha, Apium graveolens, and Nigella sativa are extracts which in preclinical trial can reduce uric acid serum, increase urinary uric acid excretion. Allopurinol is an inhibitor of the xanthine oxidase enzyme which can also reduce
Bantar Sutoko, Rakhma Yanti Hellmi, Ika Vemillia W, Stepanus Agung L   +3 more
doaj   +1 more source

Challenges of Parents While Providing Complex Medical Care at Home to Children With Cancer: A Cross‐Sectional Convergent Mixed Methods Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore challenges parents of children with cancer encounter while providing complex medical care at home. Methods Design: Cross‐sectional convergent mixed‐methods study. Instruments: Questionnaire and open interviews that mirrored and complemented each other.
Rachel Klausner Shyman, Sveta Roberman, Gal Goldstein, Sabaa Masarwe, Amy Solnica, Rachel Yaffa Zisk‐Rony   +5 more
wiley   +1 more source

Treatment with Allopurinol is Associated with Lower Risk of Acute Kidney Injury in Patients with Gout: A Retrospective Analysis of a Nested Cohort [PDF]

, 2017
Gout is characterized by recurrent episodes of acute inflammation of joint structures, called gout flares, and flares are commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs).
Pérez Ruiz, Fernando
core   +2 more sources

Increasing Rumen Microbial Diversity in Goats Favours the Adaptation to High‐Concentrate Diets With Minor Effects on Feed Utilization

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Evolution has enabled ruminants to develop a complex rumen microbiota that aids in the digestion of fibrous feeds. This study examines whether promoting a highly diverse rumen microbiota during early life continues to offer long‐term benefits in modern dairy production systems, where young ruminants are reared without exposure to adult ...
Alejandro Belanche, Juan Manuel Palma‐Hidalgo, David R. Yáñez‐Ruiz   +2 more
wiley   +1 more source

Allopurinol reduces oxidative stress and activates Nrf2/p62 to attenuate diabetic cardiomyopathy in rats [PDF]

, 2019
Jierong Luo, Dan Yan, Sisi Li, Shiming Liu, Fei Zeng, Chi Wai Cheung, Hong Liu, Michael G. Irwin, Huansen Huang, Zhengyuan Xia   +9 more
openalex   +1 more source

The Outcomes of Patients With Hyperuricemia After Total Knee Arthroplasty: A Retrospective Cohort Study

Orthopaedic Surgery, EarlyView.
Hyperuricemia elevates CRP and impairs mid‐term functional outcomes in TKA patients, with no impact on postoperative temperature. ABSTRACT Objective Hyperuricemia, characterized by elevated serum uric acid levels without acute gout symptoms, may influence postoperative outcomes after total knee arthroplasty (TKA).
Jincong Yu, Tingting Mi, Zheyuan Shao, Xuding Yan   +3 more
wiley   +1 more source

Effect of Allopurinol in Decreasing Proteinuria in Type 2 Diabetic Patients [PDF]

, 2010
Introduction. Diabetic nephropathy is the most prevalent cause of end-stage renal disease. Besides factors such as angiotensin II, cytokines, and vascular endothelial growth factor, uric acid may play a role as the underlying cause of diabetic ...
Kheiri, Soleiman., Momeni, Ali., Seirafian, Shiva., Shahidi, Shahrzad., Taheri, Shahram.   +4 more
core  

Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains

Experimental Physiology, EarlyView.
Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage, Tyler Coblentz, Saina S. Prabhu, Nicole M. Eminhizer, Ryan Childers, Randall W. Bryner, Sara E. Lewis, Brooke A. Maxwell, Evan R. DeVallance, Eric E. Kelley, Paul D. Chantler   +10 more
wiley   +1 more source