Results 11 to 20 of about 21,706 (181)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Skin rash, eosinophilia, and renal impairment in a patient recently started on allopurinol

open access: yesJournal of Family Medicine and Primary Care, 2016
Allopurinol is a hypoxanthine analog which inhibits xanthine oxidase, it is a widely used medication for the treatment of hyperuricemia and gout. Allopurinol-induced drug-induced rash with eosinophilia and systemic symptoms syndrome is an infrequent ...
Ashraf Jmeian   +4 more
doaj   +1 more source

Effects of Allopurinol as a xanthine oxidase inhibitor on depressive-like behavior of rats and changes in serum BDNF level

open access: yesIBRO Neuroscience Reports, 2022
Background: Depression is a psychiatric disorder characterized by low mood and loss of interest in daily activities. Allopurinol, a xanthine oxidase blocker, is widely administered for the treatment of hyperuricemia.
Mahsa Hadipour Jahromy   +2 more
doaj   +1 more source

Examining the use of allopurinol: Perspectives from recent drug injury relief applications

open access: yesJournal of the Formosan Medical Association, 2019
Background/purpose: Previous studies have reported that the indication and starting dose of allopurinol may be associated with the incidence of hypersensitive reactions.
Chu-Han Huang, Mei-Pei Chu, Wen-Wen Chen
doaj   +1 more source

Comparative Study of Allopurinol and Uralyt-4 in patients with Hyperuricemia in Diyala Governorate.

open access: yesمجلة كلية الطب, 2014
Background: Hyperuricemia represents a major public health problem; approximately most population has hyperuricemia, serum uric acid ≥6.5 mg/dL in women and ≥7.0 mg/dL in men.
Zuhir M. Hussein   +2 more
doaj   +1 more source

Allopurinol-Induced Stevens–Johnson Syndrome in Javanese Men With Positive HLA‐B*58:01

open access: yesFrontiers in Genetics, 2022
Background: Allopurinol is the most commonly used drug for the treatment of gout arthritis. However, the use of allopurinol is associated with severe cutaneous adverse reactions (SCARs) and life-threatening immune-mediated reactions that include Stevens ...
Astri Ferdiana   +8 more
doaj   +1 more source

Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia.

open access: yesPLoS ONE, 2015
Allopurinol, an inhibitor of xanthine oxidase, has been used in clinical trials of patients with cardiovascular and chronic kidney disease. These are two pathologies with extensive links to hypoxia and activation of the transcription factor hypoxia ...
Yu Sun   +3 more
doaj   +1 more source

Allopurinol reduces antigen-specific and polyclonal activation of human T cells

open access: yesFrontiers in Immunology, 2012
Allopurinol is the most popular commercially available xanthine oxidase inhibitor and it is widely used for treatment of symptomatic hyperuricaemia, or gout. Although, several anti-inflammatory actions of allopurinol have been demonstrated in vivo and in
Damián ePérez-Mazliah   +7 more
doaj   +1 more source

Comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults: a propensity-matched analysis

open access: yesArthritis Research & Therapy, 2018
Background The purpose of this study was to assess the comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults.
Jasvinder A. Singh, John D. Cleveland
doaj   +1 more source

Prevention effect of allopurinol on post-endoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis of prospective randomized controlled trials. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP) which can be severe and cause death in approximately 10% of cases.
Wei-Li Cao   +4 more
doaj   +1 more source

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