Results 21 to 30 of about 20,877 (183)

Comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults: a propensity-matched analysis

Arthritis Research & Therapy, 2018
Background The purpose of this study was to assess the comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults.
Jasvinder A. Singh, John D. Cleveland
doaj   +1 more source

Prevention effect of allopurinol on post-endoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis of prospective randomized controlled trials. [PDF]

PLoS ONE, 2014
BACKGROUND: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP) which can be severe and cause death in approximately 10% of cases.
Wei-Li Cao, Wen-Shan Yan, Xiao-Hui Xiang, Kai Chen, Shi-Hai Xia   +4 more
doaj   +1 more source

HLA-B*58:01 for allopurinol-induced cutaneous adverse drug reactions: Implication for clinical interpretation in Thailand

Frontiers in Pharmacology, 2016
Background: The aim of this study was to investigate the predisposition to different types of allopurinol-induced cutaneous adverse drug reactions (CADR), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) (SJS-TEN, n=13), drug ...
Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, ํYaowaluck Hongkaew, Thawinee Jantararoungtong, Thawinee Jantararoungtong, Parnrat Kuntawong, Apichaya Puangpetch, Apichaya Puangpetch, Napatrupron Koomdee, Napatrupron Koomdee, Patompong Satapornpong, Patcharin Supapsophon, Jettanong Klaewsongkram, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Ticha Rerkpattanapipat   +16 more
doaj   +1 more source

Evaluation of analgesic activity of allopurinol and febuxostat in experimental analgesic models in mice

Indian Journal of Pain, 2015
Background: Allopurinol and febuxostat are xanthine oxidase inhibitors which are used in the treatment of hyperuricemia and gout. Pain is one of the important symptoms in gout patients.
Promod D Shankpal, J H Hotwani, Kunal A Chitnis, Dnyanesh S Tadke, Vijay R Kokani   +4 more
doaj   +1 more source

Effect of low dose allopurinol on glycemic control and glycemic variability in patients with type 2 diabetes mellitus: A cross-sectional study

Heliyon, 2022
Background: Type 2 diabetes mellitus (DM), gout, and asymptomatic hyperuricemia are inter-connected pathologies. Glycemic control (GC), involving a range of treatments is central to the management of DM, whereas allopurinol continues to be the most ...
Manal M. Alem
doaj   +1 more source

Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses

Molecular Oncology, 2019
The ability to predict responsiveness to drugs in individual patients is limited. We hypothesized that integrating molecular information from databases would yield predictions that could be experimentally tested to develop transcriptomic signatures for ...
Iman Tavassoly, Yuan Hu, Shan Zhao, Chiara Mariottini, Aislyn Boran, Yibang Chen, Lisa Li, Rosa E. Tolentino, Gomathi Jayaraman, Joseph Goldfarb, James Gallo, Ravi Iyengar   +11 more
doaj   +1 more source

Allopurinol use associated with increased risk of acute myocardial infarction in older people in a case–control study

Tzu Chi Medical Journal, 2019
Objective: There is controversy about the association between the allopurinol use and the risk of acute myocardial infarction. The aim of the study was to examine the association between allopurinol use and acute myocardial infarction in older people in
Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai   +2 more
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Allopurinol in combination with thiopurine induces mucosal healing and improves clinical and metabolic outcomes in IBD

Therapeutic Advances in Gastroenterology, 2017
Background: Thiopurines, azathioprine (AZA) and 6-mercaptopurine (6-MP) are common maintenance medications for inflammatory bowel disease (IBD).
Brigitte Moreau, Pierre Clement, Yves Theoret, Ernest G. Seidman   +3 more
doaj   +1 more source