Allopurinol reduces antigen-specific and polyclonal activation of human T cells
Frontiers in Immunology, 2012 Allopurinol is the most popular commercially available xanthine oxidase inhibitor and it is widely used for treatment of symptomatic hyperuricaemia, or gout. Although, several anti-inflammatory actions of allopurinol have been demonstrated in vivo and in
Damián ePérez-Mazliah +7 more
doaj +1 more source
Comparative Study of Allopurinol and Uralyt-4 in patients with Hyperuricemia in Diyala Governorate.
مجلة كلية الطب, 2014 Background: Hyperuricemia represents a major public health problem; approximately most population has hyperuricemia, serum uric acid ≥6.5 mg/dL in women and ≥7.0 mg/dL in men.
Zuhir M. Hussein +2 more
doaj +1 more source
Allopurinol-Induced Stevens–Johnson Syndrome in Javanese Men With Positive HLA‐B*58:01
Frontiers in Genetics, 2022 Background: Allopurinol is the most commonly used drug for the treatment of gout arthritis. However, the use of allopurinol is associated with severe cutaneous adverse reactions (SCARs) and life-threatening immune-mediated reactions that include Stevens ...
Astri Ferdiana +8 more
doaj +1 more source
How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial [PDF]
, 2012 Background: Patients with chronic kidney disease (CKD) are at increased risk for inappropriate or potentially harmful prescribing. The aim of this study was to examine whether a multifaceted intervention including the use of a software programme for the ...
Beyer, Martin +7 more
core +1 more source
Arthritis Research & Therapy, 2018 Background The purpose of this study was to assess the comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults.
Jasvinder A. Singh, John D. Cleveland
doaj +1 more source
Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]
, 2017 Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C +8 more
core +5 more sources
Scientific Reports, 2020 Whether the clinical trial treatment effect of urate-lowering therapy (ULT) in patient with chronic kidney disease (CKD) is generalizable to real-word settings is unclear.
Yueh-Lung Peng +6 more
semanticscholar +1 more source
Prevention effect of allopurinol on post-endoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis of prospective randomized controlled trials. [PDF]
PLoS ONE, 2014 BACKGROUND: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP) which can be severe and cause death in approximately 10% of cases.
Wei-Li Cao +4 more
doaj +1 more source
Frontiers in Pharmacology, 2016 Background: The aim of this study was to investigate the predisposition to different types of allopurinol-induced cutaneous adverse drug reactions (CADR), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) (SJS-TEN, n=13), drug ...
Chonlaphat Sukasem +16 more
doaj +1 more source
Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress [PDF]
, 2019 York University ...
Jahng, James Won Suk +4 more
core +2 more sources