Results 81 to 90 of about 46,519 (250)
Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal [PDF]
Alexandre Perez +3 more
openalex +1 more source
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik +6 more
wiley +1 more source
Interventions for preventing oral mucositis for patients with cancer receiving treatment [PDF]
Background: Treatment of cancer with chemotherapy is becoming increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them ...
Bryan, Gemma +8 more
core +3 more sources
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters +9 more
wiley +1 more source
Objective – to study the effectiveness of Allopurinol and Quercetin inclusion in a complex treatment of stable angina pectoris and peculiarities of biomarkers and homeostatic indices changes. Materials and Methods.
V.K. Tashchuk +2 more
doaj +1 more source
Allopurinol: Sorrow to the marrow
Allopurinol is a xanthine oxidase inhibitor used in management of chronic gout. It acts by reducing the amount of uric acid by inhibiting purine metabolism.
U R Raaju, Siddharth Gosavi, K Sriharsha
doaj +1 more source
Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J. +2 more
core +1 more source
A regioselective synthesis of fused thiazoles was achieved via aza‐Michael cyclization of thiazolidinone derivatives with hydrazines or heteroaryl amines. Density functional theory, local reactivity indices, and molecular electrostatic potential mapping are used to explain selectivity.
Ghaferah H. Al‐Hazmi +8 more
wiley +1 more source
Objectives: To formulate an allopurinol suspension; study the chemical and physical stability of the formulation and compare the efficacy and adverse drug reactions of a 5 mg/mL allopurinol mouthwash with a placebo in the prevention of 5-fluorouracil (5 ...
P Kaewmanee +4 more
doaj
Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study). [PDF]
Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised, phase III trial.
Adler, S. +9 more
core +1 more source

