Results 81 to 90 of about 46,519 (250)

Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal [PDF]

open access: gold, 2020
Alexandre Perez   +3 more
openalex   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Interventions for preventing oral mucositis for patients with cancer receiving treatment [PDF]

open access: yes, 2003
Background: Treatment of cancer with chemotherapy is becoming increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them ...
Bryan, Gemma   +8 more
core   +3 more sources

Health‐Related Quality of Life in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis: A Qualitative Study

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters   +9 more
wiley   +1 more source

Effectiveness of Allopurinol and Quercetin inclusion in a complex treatment of stable angina pectoris – peculiarities of biomarkers and homeostatic indices changes

open access: yesZaporožskij Medicinskij Žurnal, 2017
Objective – to study the effectiveness of Allopurinol and Quercetin inclusion in a complex treatment of stable angina pectoris and peculiarities of biomarkers and homeostatic indices changes. Materials and Methods.
V.K. Tashchuk   +2 more
doaj   +1 more source

Allopurinol: Sorrow to the marrow

open access: yesJournal of Family Medicine and Primary Care, 2020
Allopurinol is a xanthine oxidase inhibitor used in management of chronic gout. It acts by reducing the amount of uric acid by inhibiting purine metabolism.
U R Raaju, Siddharth Gosavi, K Sriharsha
doaj   +1 more source

Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]

open access: yes, 2019
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J.   +2 more
core   +1 more source

Insights on Regioselective Synthesis of Fused Thiazoles: Density Functional Theory Calculations, Local Reactivity Indices, and Molecular Electrostatic Potential Analysis

open access: yesChemistryOpen, EarlyView.
A regioselective synthesis of fused thiazoles was achieved via aza‐Michael cyclization of thiazolidinone derivatives with hydrazines or heteroaryl amines. Density functional theory, local reactivity indices, and molecular electrostatic potential mapping are used to explain selectivity.
Ghaferah H. Al‐Hazmi   +8 more
wiley   +1 more source

A randomized controlled study of allopurinol mouthwash in the prevention of 5-fluorouracil-induced oral mucositis

open access: yesJournal of Health Science and Medical Research (JHSMR), 2009
Objectives: To formulate an allopurinol suspension; study the chemical and physical stability of the formulation and compare the efficacy and adverse drug reactions of a 5 mg/mL allopurinol mouthwash with a placebo in the prevention of 5-fluorouracil (5 ...
P Kaewmanee   +4 more
doaj  

Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study). [PDF]

open access: yes, 2016
Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised, phase III trial.
Adler, S.   +9 more
core   +1 more source

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