Results 31 to 40 of about 2,738 (186)
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Allorecognition behaviors in Myxomycetes respond to intraspecies factors [PDF]
Biology OpenMana Masui +2 more
doaj +2 more sources
Creation and maintenance of variation in allorecognition loci
Frontiers in Immunology, 2011 Allorecognition is the ability of an organism to differentiate self or close relatives from unrelated individuals. Effective allorecognition systems are critical to the survival of organisms; they prevent inbreeding, protect against pathogens, and ...
Marie Louise Nydam, Tony eDe Tomaso
doaj +1 more source
Invertebrate allorecognition [PDF]
Current Biology, 2019 Most colonial marine invertebrates live as surface encrustations in benthic environments. As they grow, these animals frequently encounter other members of their own species. These encounters typically lead to conflict, in which the colonies aggressively compete for space, or co-existence, in which the colonies peacefully border each other.
openaire +2 more sources
Invertebrate Allorecognition: The Origins of Histocompatibility [PDF]
Current Biology, 2009 Alloimmune specificity and histocompatibility, driven by genetic polymorphism, are ancient determinants of self-/non-self-recognition. Recent molecular genetic evidence has revealed an allodeterminant in the cnidarian Hydractinia that consistently predicts histocompatibility reactions.
Dishaw, Larry J., Litman, Gary W.
openaire +2 more sources
Nature Reviews Immunology, 2017 My interest in uterine natural killer (NK) cells began in the early 1990s, when I and others described the striking accumulation of NK cells in the uterine mucosa during the establishment of the placenta. Whilst working as a reproductive pathologist, I had become intrigued by pre-eclampsia, a mysterious syndrome that only occurs in pregnant women.
openaire +2 more sources
T Cell Allorecognition via Molecular Mimicry [PDF]
Immunity, 2009 T cells often alloreact with foreign human leukocyte antigens (HLA). Here we showed the LC13 T cell receptor (TCR), selected for recognition on self-HLA-B( *)0801 bound to a viral peptide, alloreacts with B44 allotypes (HLA-B( *)4402 and HLA-B( *)4405) bound to two different allopeptides.
Macdonald, Whitney A. +18 more
openaire +3 more sources
Membrane attack complexes, endothelial cell activation, and direct allorecognition
Frontiers in Immunology, 2022 Endothelial cells (ECs) form a critical immune interface regulating both the activation and trafficking of alloreactive T cells. In the setting of solid organ transplantation, donor-derived ECs represent sites where alloreactive T cells encounter major ...
Guiyu Song +15 more
doaj +1 more source
What Is Direct Allorecognition? [PDF]
Current Transplantation Reports, 2016 Direct allorecognition is the process by which donor-derived major histocompatibility complex (MHC)-peptide complexes, typically presented by donor-derived 'passenger' dendritic cells, are recognised directly by recipient T cells. In this review, we discuss the two principle theories which have been proposed to explain why individuals possess a high ...
Boardman, Dominic A +4 more
openaire +5 more sources
Clinical and Developmental Immunology, 2008 Human pregnancy poses a fundamental immunological problem because the placenta and fetus are genetically different from the host mother. Classical transplantation theory has not provided a plausible solution to this problem.
Amy Lightner +3 more
doaj +1 more source