Results 51 to 60 of about 2,738 (186)
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Understanding the mechanisms that sustain immunological nonreactivity is essential for maintaining tissue in syngeneic and allogeneic settings, such as transplantation and pregnancy tolerance.
Oron Goldstein +7 more
doaj +1 more source
Summary Background Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.
A. Merchan Muñoz +7 more
wiley +1 more source
Alloantibody Generation and Effector Function Following Sensitization To Human Leukocyte Antigen
Allorecognition is the activation of the adaptive immune system to foreign Human Leukocyte Antigen (HLA) resulting in the generation of alloantibodies.
Michelle J Hickey +2 more
doaj +1 more source
Genetic Diversity of Sexually Propagated Corals Is Maintained From the Aquarium to the Reef
ABSTRACT Amidst global reef declines, large‐scale coral aquaculture is being developed to support reef intervention. Genetic diversity underpins population resilience and therefore it is critical that aquaculture methods maintain diversity. However, it remains unclear how genetic diversity of coral progeny is shaped by (1) parental genetic composition,
Genevieve Dallmeyer‐Drennen +4 more
wiley +1 more source
Fifty Years of Natural Killer Cells: Milestones and Future Horizons
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Andreas Lundqvist +7 more
wiley +1 more source
ABSTRACT While transplantation outcomes are closely linked to HLA compatibility, minor histocompatibility antigens (mHAgs)—peptides embedded in HLA molecules bearing amino acid differences within the donor/recipient pair—also contribute to T‐cell alloreactivity, especially in HLA‐matched pairs.
Adèle Dhuyser +6 more
wiley +1 more source
Organ Transplantation: Current Status, Challenges, and Future Prospects
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
Colony specificity in Botrylloides leachi. II. Cellular aspects of the non-fusion reaction [PDF]
We continued our study on fusion and non-fusion reactions in the compound ascidian Botrylloides leachi with particular attention to the role of hemocytes in the induction of the strong cytotoxic reaction observed when genetically incompatible colonies ...
L Ballarin, G Zaniolo
doaj +1 more source
Abstract Introduction Restoring coral reefs through larval enhancement has the potential to scale interventions beyond experimental plots of tens of m2. However, the effectiveness of releasing larvae without confinement (“free release”) remains untested.
Marine Gouezo +9 more
wiley +1 more source

