Results 61 to 70 of about 3,437 (186)

Immunobiology of compound ascidians, with particular reference to Botryllus schlosseri: state of art [PDF]

Invertebrate Survival Journal, 2008
The phylogenetic position of invertebrate chordates closely related to vertebrates explains the increasing interest towards tunicate immunobiology. Most of the tunicates are ascidians which, like all other invertebrates, rely only on innate immunity for ...
L Ballarin
doaj   +2 more sources

Predictive Value of HLA‐Derived T‐Cell Epitope and B‐Cell Epitope Matching Algorithms for Pancreas Transplant Outcomes

Clinical Transplantation, Volume 40, Issue 9, September 2026.
ABSTRACT Background Donor/recipient HLA molecular mismatches are predictive of kidney transplant outcomes. Their role in pancreas transplantation has not been well studied. Methods We conducted a retrospective cohort study in 281 pancreas (± kidney) transplant recipients during 2000–2018, followed for average 53.8 months.
Zakieh Zare, Matthias Niemann, Kasra Shirini, Ian Booth, Bethany Dale, Richard Ugarte, Silke V. Niederhaus, Cinthia B. Drachenberg, Abdolreza Haririan   +8 more
wiley   +1 more source

Allorecognition and the alloresponse: clinical implications

Tissue Antigens, 2007
AbstractThe artificial transfer of tissues or cells between genetically diverse individuals elicits an immune response that is adaptive and specific. This response is orchestrated by T lymphocytes that are recognizing, amongst others, major histocompatibility complex (MHC) molecules expressed on the surface of the transferred cells.
Afzali, B, Lechler, R I, Hernandez Fuentes, Maria   +2 more
openaire   +3 more sources

Allorecognition and chimerism in an invertebrate model organism [PDF]

Organogenesis, 2008
The presence of highly specific histocompatibility reactions in colonial marine invertebrates that lack adaptive immune systems (such as the sponges, cnidarians, bryozoans and ascidians) provides a unique opportunity to investigate the evolutionary roots of allorecognition and to explore whether homologous innate recognition systems exist in ...
Fadi G, Lakkis, Stephen L, Dellaporta, Leo W, Buss   +2 more
openaire   +2 more sources

Salvage Therapy With Inotuzumab Ozogamicin in Relapsed/Refractory B‐ALL After CAR‐T Therapy and HSCT: A Case Series

Cancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Although inotuzumab ozogamicin (InO) has been approved as an effective agent for patients with refractory/relapsed (r/r) B‐cell acute lymphoblastic leukemia (B‐ALL), data in the context of post chimeric antigen receptor (CAR)‐T cell therapy and allogeneic hematopoietic stem cell transplantation (allo‐HSCT) relapse are lacking.
Honghu Li, Luxin Yang, Lizhen Liu, Xiaoyu Lai, Lixia Zhu, Kui Zhao, Qian Luo, He Huang, Yi Luo   +8 more
wiley   +1 more source

Colony specificity in Botrylloides leachi. II. Cellular aspects of the non-fusion reaction [PDF]

Invertebrate Survival Journal, 2007
We continued our study on fusion and non-fusion reactions in the compound ascidian Botrylloides leachi with particular attention to the role of hemocytes in the induction of the strong cytotoxic reaction observed when genetically incompatible colonies ...
L Ballarin, G Zaniolo
doaj   +2 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, Volume 4, Issue 2, June 2026.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Recall features and allorecognition in innate immunity [PDF]

Transplant International, 2017
Alloimmunity traditionally distinguishes short-lived, rapid and nonspecific innate immune responses from adaptive immune responses that are characterized by a highly specific response initiated in a delayed fashion. Key players of innate immunity such as natural killer (NK) cells and macrophages present the first-line defence of immunity.
Hirofumi Uehara, Koichiro Minami, Markus Quante, Yeqi Nian, Timm Heinbokel, Haruhito Azuma, Abdala El Khal, Stefan G. Tullius   +7 more
openaire   +2 more sources

Allorecognition by T Lymphocytes and Allograft Rejection

, 2017
Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the adaptive inflammatory immune response leading to the rejection of allogeneic transplants.
Paster, Joshua, Benichou, Gilles, Marino, Jose   +2 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, Volume 15, Issue 17, 8 May 2026.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source